Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.63 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.63 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.63 |
| ▸ | SERPINE1 | P05121 | 8/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6351469 | 0.87 | AKR1C2 (0.66) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6353963 | 0.87 | KMT2A (0.62) | MEN1KMT2AAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL19554161 | 0.85 | CA2 (0.56) | MEN1KMT2AAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6357568 | 0.85 | ALDH1A1 (0.70) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6359203 | 0.85 | KMT2A (0.58) | MEN1KMT2AAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6359497 | 0.85 | KMT2A (0.53) | MEN1KMT2AAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6819989 | 0.83 | ALB (0.54) | MEN1KMT2AAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6357140 | 0.83 | MEN1 (0.60) | MEN1KMT2AAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6349507 | 0.83 | MEN1 (0.57) | MEN1KMT2AAKR1C2AKR1C1SERPINE1 | |
| SCHEMBL6353195 | 0.83 | KMT2A (0.52) | MEN1KMT2AAKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | MEN1 3274/4885KMT2A 3645/4885CYP1A2 2118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.