Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944346 | 0.81 | HCAR2 (0.47) | KIF11KMT2AANPEPENPEPCYP1A2 | |
| SCHEMBL9717076 | 0.81 | KIF11 (0.58) | KIF11ANPEPENPEPCYP1A2CYP2D6 | |
| SCHEMBL10336616 | 0.78 | KIF11 (0.43) | KIF11KMT2AANPEPENPEPCYP1A2 | |
| SCHEMBL17540887 | 0.77 | ALDH1A1 (0.52) | CYP1A2SMN1; SMN2NPSR1TSHRALDH1A1 | |
| SCHEMBL28623093 | 0.76 | KMT2A (0.47) | KMT2AMEN1CYP3A4MAPK1PTGS1 | |
| SCHEMBL113808 | 0.75 | CYP2D6 (0.46) | KMT2ACYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL986067 | 0.75 | KMT2A (0.48) | KMT2ACYP2D6CYP3A4TSHRMAPK1 | |
| SCHEMBL286685 | 0.75 | KMT2A (0.48) | KMT2ACYP2D6CYP3A4TSHRMAPK1 | |
| SCHEMBL31097897 | 0.74 | KMT2A (0.42) | KMT2ACYP1A2CYP2D6MEN1 | |
| SCHEMBL4587552 | 0.74 | KIF11 (0.39) | KIF11ANPEPENPEPCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960881-A | REACTING AMINO ACID WITH ALPHA-CHLORINATED CARBONATE IN SOLVENT IN PRESENCE OF ACID SCAVENGER | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1990-10-02 | — | — | US | claimed |
| US-20050096456-A1 | Compounds comprising pseudo-amino acids | ADPRO TECH LIMITED (GB) | 2005-05-05 | — | — | US | disclosed |
| US-20050090651-A1 | Polymeric compounds | ADPROTECH LIMITED CESTERFORD RESEARCH PARK, LITTLE CHESTERFORD SAFFR (GB) | 2005-04-28 | — | — | US | disclosed |
| EP-1487860-A1 | COMPOUNDS COMPRISING PSEUDO-AMINO ACIDS | AdProTech Limited (GB) | 2004-12-22 | — | — | EP | disclosed |
| EP-1432727-A2 | TRIMERIC CONJUGATES OF PEPTIDIC DERIVATIVE | AdProTech Limited (GB) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003080650-A1 | COMPOUNDS COMPRISING PSEUDO-AMINO ACIDS | ADPROTECH LIMITED (GB) | 2003-10-02 | — | — | WO | disclosed |
| WO-2003027137-A2 | TRIMERIC CONJUGATES OF PEPTIDIC DERIVATIVE | ADPROTECH LIMITED (GB) | 2003-04-03 | — | — | WO | disclosed |
| US-4960881-A | REACTING AMINO ACID WITH ALPHA-CHLORINATED CARBONATE IN SOLVENT IN PRESENCE OF ACID SCAVENGER | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1990-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096456-A1 | Compounds comprising pseudo-amino acids | QPCTL, LNPEP, QPCT | KIF11 4586/4885KMT2A 1913/4885ANPEP 10/4885 |
| US-20050090651-A1 | Polymeric compounds | TST, TMT1A, CBS | KIF11 3692/4885KMT2A 3377/4885ANPEP 2373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.