SCHEMBL6358240

SCHEMBL6358240

CC(C)CNCc1cccc(B(O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 6/20 0.51
LPL P06858 2/20 0.47
LIPG Q9Y5X9 2/20 0.47
CA2 P00918 3/20 0.44
MAP4K4 O95819 1/20 0.40
PSMB5 P28074 3/20 0.40
BCHE P06276 1/20 0.39
LMNA P02545 1/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CXCR1 P25024 1/20 0.38
CXCR2 P25025 1/20 0.38
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15859356 0.82 CA2 (0.49) CA2MAP4K4BCHELMNAALDH1A1
SCHEMBL15981401 0.80 ENPP2 (0.55) ENPP2LPLLIPGCA2PSMB5
SCHEMBL6352816 0.80 ENPP2 (0.58) ENPP2LPLLIPGPSMB5BCHE
SCHEMBL6351213 0.80 LPL (0.53) LPLLIPGCA2ALDH1A1
SCHEMBL3724201 0.78 ENPP2 (0.60) ENPP2LPLLIPGALDH1A1KDM4E
SCHEMBL3786247 0.78 ENPP2 (0.60) ENPP2LPLLIPGALDH1A1KDM4E
SCHEMBL14492262 0.76 DNM1 (0.52) CA2MAP4K4BCHEALDH1A1KDM4E
SCHEMBL1722682 0.75 ENPP2 (0.53) ENPP2LPLLIPGPSMB5ALDH1A1
SCHEMBL3972644 0.75 ENPP2 (0.52) ENPP2LPLLIPGPSMB5ALDH1A1
SCHEMBL21125600 0.75 LPL (0.60) ENPP2LPLLIPGALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919382-B2 Preparation and uses of conjugated solid supports for boronic acids THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2005-07-19 US disclosed
US-20030044840-A1 Preparation and uses of conjugated solid supports for boronic acids GOVERNORS OF THE UNIVERSITY OF ALBERTA, THE (CA) 2003-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030044840-A1 Preparation and uses of conjugated solid supports for boronic acids SLC43A1, SBDS, SLC7A5 ENPP2 3898/4885LPL 4731/4885LIPG 4136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.