Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 6/20 | 0.62 |
| ▸ | AKR1C1 | Q04828 | 6/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.49 |
| ▸ | MYC | P01106 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.47 |
| ▸ | MAX | P61244 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359602 | 0.91 | AKR1C2 (0.55) | AKR1C2AKR1C1AKR1C3MYCMEN1 | |
| SCHEMBL6349305 | 0.86 | AKR1C2 (0.66) | AKR1C2AKR1C1AKR1C3AKR1C4MEN1 | |
| SCHEMBL6359133 | 0.84 | AKR1C2 (0.68) | AKR1C2AKR1C1AKR1C3AKR1C4MYC | |
| SCHEMBL6357045 | 0.82 | AKR1C2 (0.74) | AKR1C2AKR1C1AKR1C3AKR1C4MEN1 | |
| SCHEMBL6358657 | 0.81 | AKR1C2 (0.72) | AKR1C2AKR1C1AKR1C3AKR1C4MEN1 | |
| SCHEMBL6352019 | 0.81 | AKR1C2 (0.78) | AKR1C2AKR1C1AKR1C3AKR1C4MEN1 | |
| SCHEMBL6353682 | 0.79 | AKR1C2 (0.71) | AKR1C2AKR1C1MEN1KMT2AMAPT | |
| SCHEMBL6352473 | 0.78 | AKR1C2 (0.77) | AKR1C2AKR1C1AKR1C3AKR1C4MEN1 | |
| SCHEMBL6352870 | 0.78 | AKR1C2 (0.70) | AKR1C2AKR1C1AKR1C3AKR1C4MEN1 | |
| SCHEMBL6358257 | 0.78 | MAOB (0.58) | AKR1C2AKR1C1AKR1C3AKR1C4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | AKR1C2 3012/4885AKR1C1 2615/4885AKR1C3 3288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.