SCHEMBL6359459

SCHEMBL6359459

c1ccc(Oc2ccccc2B(c2ccccc2Oc2ccccc2)c2ccccc2Oc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
GAA P10253 1/20 0.52
KMT2A Q03164 1/20 0.52
LTA4H P09960 3/20 0.50
TSHR P16473 2/20 0.50
HRH1 P35367 1/20 0.44
CTNNB1 P35222 1/20 0.44
SLC6A2 P23975 3/20 0.43
SLC6A4 P31645 3/20 0.43
ALDH1A1 P00352 2/20 0.43
HTR1A P08908 2/20 0.43
SLC6A3 Q01959 2/20 0.43
HTT P42858 2/20 0.43
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
RIPK1 Q13546 1/20 0.42
HPGD P15428 1/20 0.42
KDM1A O60341 2/20 0.41
DPP4 P27487 1/20 0.41
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20600 0.82 ENPP2 (0.59) LMNAGAAKMT2ALTA4HTSHR
SCHEMBL29889491 0.82 ENPP2 (0.59) LMNAGAAKMT2ALTA4HTSHR
SCHEMBL9946021 0.82 LMNA (0.48) LMNAGAAKMT2ALTA4HTSHR
SCHEMBL51822 0.79 LTA4H (0.69) LMNAGAAKMT2ALTA4HTSHR
SCHEMBL3893178 0.76 LTA4H (0.65) LMNAGAAKMT2ALTA4HTSHR
Bromide SCHEMBL8447011 0.76 LTA4H (0.65) LMNAGAAKMT2ALTA4HTSHR
SCHEMBL5852017 0.76 LTA4H (0.65) LMNAGAAKMT2ALTA4HTSHR
SCHEMBL9264065 0.76 LTA4H (0.65) LMNAGAAKMT2ALTA4HTSHR
Ammonia Solution, Strong SCHEMBL7127955 0.76 LTA4H (0.65) LMNAGAAKMT2ALTA4HTSHR
SCHEMBL3893171 0.76 ALDH1A1 (0.67) LMNAGAAKMT2ALTA4HTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050118209-A1 Cosmetic or dermatological preparations for preventing damages to skin caused by peroxides BASF AKTIENGESELLSCHAFT (DE) 2005-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050118209-A1 Cosmetic or dermatological preparations for preventing damages to skin caused by peroxides CAT, LPO, GPX4 LMNA 751/4885GAA 847/4885KMT2A 2682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.