Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9930684 | 0.73 | CCR2 (0.67) | CCR2BRAF | |
| SCHEMBL15037433 | 0.72 | KEAP1 (0.53) | MAPTNPSR1ALDH1A1ALDH3A1SMN1; SMN2 | |
| SCHEMBL15009060 | 0.72 | ALDH1A1 (0.57) | MAPTNPSR1ALDH1A1HTTALDH3A1 | |
| SCHEMBL6363753 | 0.71 | MAPT (0.47) | MAPTNPSR1ALDH1A1ALDH3A1KMT2A | |
| SCHEMBL4966705 | 0.71 | NR1H3 (0.50) | MAPTALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL15009245 | 0.71 | MAPT (0.51) | MAPTNPSR1ALDH1A1HTTCCR2 | |
| SCHEMBL15009688 | 0.70 | ALDH1A1 (0.49) | ALDH1A1HTTNPC1SMN1; SMN2TP53 | |
| SCHEMBL4969872 | 0.70 | ALDH1A1 (0.49) | MAPTALDH1A1HTTALDH3A1SMN1; SMN2 | |
| SCHEMBL31361989 | 0.69 | MAPT (0.72) | MAPTNPSR1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4969877 | 0.69 | MEN1 (0.56) | ALDH1A1HTTSMN1; SMN2TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288324-A1 | Aromatic sulfonamides as peroxynitrite-rearrangement catalysts | BLUME THORSTEN | 2005-12-29 | — | — | US | claimed |
| US-20050288324-A1 | Aromatic sulfonamides as peroxynitrite-rearrangement catalysts | BLUME THORSTEN | 2005-12-29 | — | — | US | disclosed |
| US-6946466-B2 | Aromatic sulfonamides as peroxynitrite-rearrangement catalysts | SCHERING AG (DE) | 2005-09-20 | — | — | US | disclosed |
| WO-2004089882-A2 | AROMATIC SULFONAMIDES AS PEROXYNITRITE-REARRANGEMENT CATALYSTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-10-21 | — | — | WO | disclosed |
| US-20040204452-A1 | Aromatic sulfonamides as peroxynitrite-rearrangement catalysts | SCHERING AG (DE) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288324-A1 | Aromatic sulfonamides as peroxynitrite-rearrangement catalysts | SQOR, GSR, PPOX | MAPT 2502/4885NPSR1 251/4885ALDH1A1 496/4885 |
| US-20040204452-A1 | Aromatic sulfonamides as peroxynitrite-rearrangement catalysts | SQOR, NOX1, GSR | MAPT 2315/4885NPSR1 281/4885ALDH1A1 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.