Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951641 | 0.93 | CYP2C19 (0.39) | CYP2C19HIF1AELANEALDH1A1KDM4E | |
| SCHEMBL519802 | 0.87 | ENPP2 (0.41) | PDK2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL29469063 | 0.87 | ENPP2 (0.41) | PDK2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5079740 | 0.81 | PDK2 (0.42) | PDK2PDK1PDK3PDK4CYP2C19 | |
| SCHEMBL1275130 | 0.77 | CES1 (0.48) | KDM4EMAPK1ENPP2 | |
| SCHEMBL16722809 | 0.76 | ALDH1A1 (0.47) | CYP2C19HIF1AELANEALDH1A1KDM4E | |
| SCHEMBL15445468 | 0.76 | ELANE (0.47) | CYP2C19HIF1AELANEALDH1A1KDM4E | |
| SCHEMBL29085598 | 0.75 | LMNA (0.41) | PDK2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL13863275 | 0.75 | SMN1; SMN2 (0.43) | ALDH1A1KDM4ELMNASMN1; SMN2KMT2A | |
| SCHEMBL28063627 | 0.72 | ENPP2 (0.40) | ALDH1A1SMN1; SMN2KMT2AENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |