Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.33 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951647 | 0.93 | ELANE (0.46) | ELANEALDH1A1KCNN4HSD11B1CA4 | |
| SCHEMBL651370 | 0.88 | ORAI1 (0.42) | ELANEALDH1A1CA4CA6CA5A | |
| SCHEMBL1275132 | 0.75 | CES1 (0.41) | ELANEKCNN4CA4CA6CA5A | |
| SCHEMBL18424371 | 0.72 | CYP2C19 (0.39) | ELANEALDH1A1HSD11B1CA4CA6 | |
| SCHEMBL1672441 | 0.72 | ORAI1 (0.46) | ALDH1A1CA4CA6CA5ACA7 | |
| SCHEMBL28524847 | 0.70 | ELANE (0.44) | ELANEALDH1A1CA4CA6CA5A | |
| SCHEMBL28664851 | 0.70 | TRPV6 (0.44) | ALDH1A1CA4CA6CA5ACA7 | |
| SCHEMBL9621660 | 0.70 | ALDH1A1 (0.44) | ELANEALDH1A1CA4CA6CA5A | |
| SCHEMBL13475992 | 0.70 | ORAI1 (0.48) | ELANEALDH1A1CA4CA6CA5A | |
| SCHEMBL1237453 | 0.69 | KMT2A (0.42) | ALDH1A1KCNN4CA4CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |