Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.42 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.42 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.42 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.42 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6375208 | 0.88 | ELANE (0.41) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL1672441 | 0.82 | ORAI1 (0.46) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL28524847 | 0.80 | ELANE (0.44) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL9621660 | 0.80 | ALDH1A1 (0.44) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL13475992 | 0.80 | ORAI1 (0.48) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL28664851 | 0.80 | TRPV6 (0.44) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL1237453 | 0.79 | KMT2A (0.42) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL20916961 | 0.78 | LMNA (0.54) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL384014 | 0.78 | ORAI1 (0.42) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL9982901 | 0.78 | TRPV6 (0.42) | ORAI1ORAI2ORAI3TRPV6PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12116698-B1 | Protein surface recognition via chemically enhanced phage display | THE TRUSTEES OF BOSTON COLLEGE (MA) | 2024-10-15 | — | — | US | claimed |
| CN-117126185-A | Difluoro boron beta-diketonate complex fluorescent probe and preparation method and application thereof | 西北工业大学深圳研究院 | 2023-11-28 | — | — | CN | claimed |
| US-11655468-B2 | Methods and compositions of chemically modified phage libraries | THE TRUSTEES OF BOSTON COLLEGE (MA) | 2023-05-23 | — | — | US | claimed |
| CN-111171721-B | Ceramizable ablation-resistant coating and preparation method thereof | 西安近代化学研究所 | 2021-08-20 | — | — | CN | claimed |
| CN-111171721-A | Ceramizable ablation-resistant coating and preparation method thereof | 西安近代化学研究所 | 2020-05-19 | — | — | CN | claimed |
| US-8119680-B2 | α-Haloketone derivatives of imidazolyl-substituted aromatic compounds and compounds prepared therefrom | NEUROGENETIC PHARMACEUTICALS, INC. (US) | 2012-02-21 | — | — | US | claimed |
| US-20100331551-A1 | ALPHA-HALOKETONE DERIVATIVES OF IMIDAZOLYL-SUBSTITUTED AROMATIC COMPOUNDS AND COMPOUNDS PREPARED THEREFROM | NEUROGENETIC PHARMACEUTICALS, INC | 2010-12-30 | — | — | US | claimed |
| CN-120817797-B | High-temperature heat-insulating refractory material for kiln and preparation method thereof | 安徽瑞泰新材料科技有限公司 | 2025-11-14 | — | — | CN | disclosed |
| CN-120817797-A | High-temperature heat-insulating refractory material for kiln and preparation method thereof | 安徽瑞泰新材料科技有限公司 | 2025-10-21 | — | — | CN | disclosed |
| US-12258331-B2 | Pyrimidine derivative and preparation process and use thereof | GUANGDONG LEWWIN PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. (CN) | 2025-03-25 | — | — | US | disclosed |
| US-12202820-B2 | Pyrimidine derivative and preparation process and use thereof | GUANGDONG LEWWIN PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. (CN) | 2025-01-21 | — | — | US | disclosed |
| US-12168654-B2 | Pyrimidine derivative containing one deuterium atom and preparation process and use thereof | GUANGDONG LEWWIN PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. (CN) | 2024-12-17 | — | — | US | disclosed |
| CN-117126185-A | Difluoro boron beta-diketonate complex fluorescent probe and preparation method and application thereof | 西北工业大学深圳研究院 | 2023-11-28 | — | — | CN | disclosed |
| WO-2006028875-A1 | PHENANTHRIDINE CARBONYL PHENOLS AS CYTOKINE MODULATORS | WYETH (US) | 2006-03-16 | — | — | WO | disclosed |
| WO-2006001150-A1 | POLYMER LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT EMITTING ELEMENT | SHOWA DENKO K.K. (JP) | 2006-01-05 | — | — | WO | disclosed |
| US-6963017-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2005-11-08 | — | — | US | disclosed |
| EP-1569637-A1 | BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS | Abbott Laboratories (US) | 2005-09-07 | — | — | EP | disclosed |
| US-20050033076-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2005-02-10 | — | — | US | disclosed |
| WO-2004043458-A1 | BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2004-05-27 | — | — | WO | disclosed |
| US-20030009046-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12202820-B2 | Pyrimidine derivative and preparation process and use thereof | MET, HCCS, MTR | ORAI1 3092/4885ORAI2 4056/4885ORAI3 3343/4885 |
| US-12116698-B1 | Protein surface recognition via chemically enhanced phage display | APBA1, CLTB, APMAP | ORAI1 3190/4885ORAI2 3385/4885ORAI3 3169/4885 |
| US-20050033076-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP2J2, IDH3A | ORAI1 4605/4885ORAI2 1642/4885ORAI3 2626/4885 |
| US-12258331-B2 | Pyrimidine derivative and preparation process and use thereof | MTR, HCCS, MET | ORAI1 3365/4885ORAI2 3782/4885ORAI3 3137/4885 |
| US-12168654-B2 | Pyrimidine derivative containing one deuterium atom and preparation process and use thereof | DUT, TYMP, DCTD | ORAI1 4213/4885ORAI2 4462/4885ORAI3 3779/4885 |
| US-20100331551-A1 | ALPHA-HALOKETONE DERIVATIVES OF IMIDAZOLYL-SUBSTITUTED AROMATIC COMPOUNDS AND COMPOUNDS PREPARED THEREFROM | HYPK, APP, NEFM | ORAI1 4216/4885ORAI2 4418/4885ORAI3 4454/4885 |
| US-11655468-B2 | Methods and compositions of chemically modified phage libraries | CLTB, PTMS, RNPEP | ORAI1 4735/4885ORAI2 4798/4885ORAI3 4813/4885 |
| US-20030009046-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP1B1, CYP1A1 | ORAI1 4577/4885ORAI2 1594/4885ORAI3 2480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.