Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784726 | 0.78 | TAAR1 (0.50) | MAPTCYP1A2CYP3A4TSHRL3MBTL1 | |
| SCHEMBL9883869 | 0.78 | TAAR1 (0.50) | MAPTCYP1A2CYP3A4TSHRL3MBTL1 | |
| SCHEMBL11065465 | 0.70 | ALDH1A1 (0.50) | CRHBPCRHR2MAPTCYP1A2CYP3A4 | |
| SCHEMBL6375440 | 0.70 | HRH3 (0.43) | MAPTTSHRMEN1KMT2APOLB | |
| SCHEMBL8285058 | 0.69 | ALDH1A1 (0.53) | CRHBPCRHR2MAPTCYP1A2CYP3A4 | |
| SCHEMBL7240855 | 0.69 | ALDH1A1 (0.53) | CRHBPCRHR2MAPTCYP1A2CYP3A4 | |
| SCHEMBL16487923 | 0.69 | MAPT (0.49) | CRHBPCRHR2MAPTCYP1A2CYP3A4 | |
| SCHEMBL8286047 | 0.69 | ALDH1A1 (0.53) | CRHBPCRHR2MAPTCYP1A2CYP3A4 | |
| SCHEMBL7860138 | 0.69 | CRHBP (0.58) | CRHBPCRHR2MAPTKCNH3MAPK1 | |
| SCHEMBL5611161 | 0.67 | NOTUM (0.44) | MAPTL3MBTL1ALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119461-A1 | Novel receptor, and compounds which bind thereto | THE UNIVERSITY OF MELBOURNE | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119461-A1 | Novel receptor, and compounds which bind thereto | GPR27, GPR174, GPR52 | IDH1 4498/4885CRHBP 837/4885CRHR2 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.