SCHEMBL6385307

SCHEMBL6385307

CC[N]c1ccc(F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.44
NOS1 P29475 2/20 0.44
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
PLAU P00749 1/20 0.41
ACHE P22303 2/20 0.39
LMNA P02545 3/20 0.37
IDO1 P14902 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
TRPA1 O75762 3/20 0.34
TAAR1 Q96RJ0 2/20 0.33
HTR7 P34969 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
ABCB11 O95342 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1735291 0.74 NOS3 (0.44) NOS3NOS1SLC22A2SLC22A1SLC22A3
SCHEMBL98201 0.74 NOS3 (0.45) NOS3NOS1ACHELMNAESR1
SCHEMBL4607389 0.74 NOS1 (0.44) NOS1SLC22A2SLC22A1SLC22A3PLAU
SCHEMBL8767212 0.74 PLAU (0.52) PLAULMNATRPA1TAAR1CA2
SCHEMBL53706 0.72
SCHEMBL6380460 0.72 NPC1 (0.46) ACHEIDO1TAAR1
SCHEMBL3571823 0.70 CA1 (0.52) NOS3NOS1ACHEIDO1CA1
Alcohol SCHEMBL28041790 0.70 ACHE (0.53) NOS3NOS1ACHELMNAIDO1
SCHEMBL1547470 0.69
SCHEMBL2090999 0.69 NOS3 (0.53) NOS3NOS1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113105334-B Perovskite single crystal and preparation method and application thereof 上海科技大学 2023-08-22 CN claimed
CN-113105334-B Perovskite single crystal and preparation method and application thereof 上海科技大学 2023-08-22 CN disclosed
CN-113105334-B Perovskite single crystal and preparation method and application thereof 上海科技大学 2023-08-22 CN disclosed
CN-113512029-B Preparation and application of substituted pyrazole compound containing pyrimidinamine 沈阳中化农药化工研发有限公司 2023-01-24 CN disclosed
CN-113512029-A Preparation and application of substituted pyrazole compound containing pyrimidinamine 沈阳中化农药化工研发有限公司 2021-10-19 CN disclosed
EP-0988309-B1 C-4''-SUBSTITUTED MACROLIDE DERIVATIVES PFIZER PROD INC (US) 2005-11-23 EP disclosed