SCHEMBL638848

SCHEMBL638848

Nc1cccc2nccc(N)c12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 1/20 0.56
AXL P30530 1/20 0.44
NR4A2 P43354 3/20 0.39
SOS2 Q07890 1/20 0.39
EGFR P00533 1/20 0.39
MAPT P10636 5/20 0.39
KDM4E B2RXH2 4/20 0.39
HSD17B10 Q99714 3/20 0.39
HIF1A Q16665 2/20 0.39
AURKA O14965 1/20 0.38
KMT2A Q03164 5/20 0.38
MEN1 O00255 4/20 0.38
LMNA P02545 2/20 0.38
BLM P54132 2/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
HTT P42858 1/20 0.38
ALDH1A1 P00352 5/20 0.36
POLB P06746 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29661918 1.00 NCF1 (0.56) NCF1AXLNR4A2SOS2EGFR
SCHEMBL4507822 0.83 NCF1 (0.44) NCF1AXLMAPTKDM4EHSD17B10
SCHEMBL10669377 0.83 NCF1 (0.48) NCF1AXLNR4A2SOS2AURKA
SCHEMBL15139040 0.83 NR4A2 (0.52) NCF1NR4A2SOS2MAPTKDM4E
SCHEMBL3574247 0.78 DCPS (0.51) NCF1EGFRKDM4EALDH1A1HPGD
SCHEMBL8781926 0.78 DCPS (0.47) NCF1KDM4EALDH1A1HPGDTDP1
SCHEMBL11159666 0.78 NCF1 (0.44) NCF1AXLNR4A2SOS2HSD17B10
Hydrochloric Acid SCHEMBL3574160 0.77 DCPS (0.50) NCF1EGFRKDM4EALDH1A1HPGD
SCHEMBL25261318 0.77 MMP2 (0.46) NCF1MAPTKDM4EHSD17B10KMT2A
SCHEMBL27789837 0.76 POLB (0.54) NCF1EGFRKDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5741908-A Process for reparing imidazoquinolinamines MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-21 US claimed
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
CN-111517902-A Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2020-08-11 CN disclosed
WO-2020155595-A1 AEROBIC OXIDATION SYSTEM CONTAINING SULFINIC ACID, SULFONIC ACID OR DERIVATIVES THEREOF AND PHOTOCATALYTIC OXIDATION METHOD THEREFOR 清华大学 2020-08-06 WO disclosed
EP-2235112-B1 SYNTHESIS OF DYES IN MIXING UNITS BASF SE (DE) 2014-03-12 EP disclosed
CN-101896555-B Synthesis of colorants in a mixing device BASF SE 2013-10-23 CN disclosed
US-8551237-B2 Synthesis of colorants in mixing apparatus BASF SE (DE) 2013-10-08 US disclosed
CN-101688063-B Aqueous synthesis of perylene pigments BASF SE 2013-04-10 CN disclosed
US-8334386-B2 Aqueous synthesis of perylene pigments BASF SE (DE) 2012-12-18 US disclosed
EP-2176356-B1 AQUEOUS SYNTHESIS OF PERYLENE PIGMENTS BASF SE (DE) 2012-02-22 EP disclosed
CN-101896555-A Synthesis of colorants in a mixing device BASF SE 2010-11-24 CN disclosed
EP-2235112-A2 SYNTHESIS OF DYES IN MIXING UNITS BASF SE (DE) 2010-10-06 EP disclosed
US-20100242792-A1 SYNTHESIS OF COLORANTS IN MIXING APPARATUS BASF SE (DE) 2010-09-30 US disclosed
US-20100184983-A1 AQUEOUS SYNTHESIS OF PERYLENE PIGMENTS BASF SE (DE) 2010-07-22 US disclosed
EP-2176356-A2 AQUEOUS SYNTHESIS OF PERYLENE PIGMENTS BASF SE (DE) 2010-04-21 EP disclosed
CN-101688063-A aqueous synthesis of perylene pigments BASF SE 2010-03-31 CN disclosed
WO-2009074504-A2 SYNTHESIS OF DYES IN MIXING UNITS BASF SE (DE) 2009-06-18 WO disclosed
WO-2009003980-A2 AQUEOUS SYNTHESIS OF PERYLENE PIGMENTS BASF SE (DE) 2009-01-08 WO disclosed
US-5693811-A Process for preparing tetrahdroimidazoquinolinamines MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100242792-A1 SYNTHESIS OF COLORANTS IN MIXING APPARATUS DDC, AOC1, DAO NCF1 1910/4885AXL 1606/4885NR4A2 3590/4885
US-20100184983-A1 AQUEOUS SYNTHESIS OF PERYLENE PIGMENTS F12, XDH, TYR NCF1 1504/4885AXL 2935/4885NR4A2 1573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.