Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834586 | 0.86 | IDO1 (0.53) | IDO1 | |
| SCHEMBL29533074 | 0.76 | SLC18A3 (0.47) | IDO1PDPK1CYP11B2RETHTR2A | |
| SCHEMBL22882915 | 0.76 | SLC18A3 (0.47) | IDO1PDPK1CYP11B2RETHTR2A | |
| SCHEMBL11671198 | 0.75 | SRD5A1 (0.55) | IDO1PDPK1CYP11B2RETHTR2A | |
| SCHEMBL29263189 | 0.73 | IDO1 (0.52) | IDO1PDPK1CYP11B2RETHTR2A | |
| Magnesium SCHEMBL31510119 | 0.73 | SRD5A1 (0.53) | IDO1PDPK1CYP11B2RETHTR2A | |
| SCHEMBL10633202 | 0.73 | IDO1 (0.52) | IDO1PDPK1CYP11B2RETHTR2A | |
| SCHEMBL8679389 | 0.73 | IDO1 (0.52) | IDO1PDPK1CYP11B2RETHTR2A | |
| SCHEMBL10877517 | 0.73 | HTR2C (0.62) | HTR2ADRD2MAOB | |
| SCHEMBL23343810 | 0.71 | IDO1 (0.50) | IDO1PDPK1CYP11B2RETHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249449-A1 | SHP2 INHIBITORS, COMPOSITIONS AND USES THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2021-12-16 | — | — | WO | disclosed |
| US-9312497-B2 | Heterocyclic compound, organic light-emitting diode including the heterocyclic compound, and flat display device including the organic light-emitting diode | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-04-12 | — | — | US | disclosed |
| EP-1745015-B1 | BICYCLIC AROMATIC SULFINYL DERIVATIVES | CEPHALON INC (US) | 2016-02-17 | — | — | EP | disclosed |
| US-8623521-B2 | Heterocyclic compound and organic light-emitting diode and flat display device including the heterocyclic compound | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-01-07 | — | — | US | disclosed |
| US-20130001527-A1 | HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE HETEROCYCLIC COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2013-01-03 | — | — | US | disclosed |
| US-20120326134-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE AND FLAT DISPLAY DEVICE INCLUDING THE HETEROCYCLIC COMPOUND | SAMSUNG DISPLAY CO., LTD. (KR) | 2012-12-27 | — | — | US | disclosed |
| US-8314155-B2 | Bicyclic aromatic sulfinyl derivatives | CEPHALON, INC (US) | 2012-11-20 | — | — | US | disclosed |
| US-8314155-B2 | Bicyclic aromatic sulfinyl derivatives | CEPHALON, INC (US) | 2012-11-20 | — | — | US | disclosed |
| US-20090042907-A1 | Bicyclic aromatic sulfinyl derivatives | CEPHALON, INC. (US) | 2009-02-12 | — | — | US | disclosed |
| US-20090042907-A1 | Bicyclic aromatic sulfinyl derivatives | CEPHALON, INC. (US) | 2009-02-12 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| EP-0802914-B1 | ARYL- AND HETEROARYL- PURINE AND PYRIDOPYRIMIDINE DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-06-06 | — | — | EP | disclosed |
| US-6051569-A | 1'S, 5R, 6R-carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5965563-A | NOVEL PURINE DERIVATIVES SUCH AS N6-(2-OXINDOL-5-YL) ADENINE, METHODS OF SYNTHESIZING THEM; USE AS TYROSINE KINASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-10-12 | — | — | US | disclosed |
| EP-0826687-A1 | Carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |
| US-5686621-A | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases | ALCON LABORATORIES, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0774465-A1 | Penem derivatives and antimicrobial agents containing the same | SUNTORY LIMITED (JP) | 1997-05-21 | — | — | EP | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-5464866-A | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases | ALCON LABORATORIES, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| WO-1994004143-A1 | SUBSTITUTED HYDRINDANES FOR THE TREATMENT OF ANGIOGENESIS-DEPENDENT DISEASES | ALCON LABORATORIES, INC. (US) | 1994-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130001527-A1 | HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE HETEROCYCLIC COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE | DDT, DLD, PPOX | IDO1 1147/4885PDPK1 1422/4885CYP11B2 616/4885 |
| US-20090042907-A1 | Bicyclic aromatic sulfinyl derivatives | SULT2A1, TPST2, AHR | IDO1 207/4885PDPK1 3714/4885CYP11B2 15/4885 |
| US-20120326134-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE AND FLAT DISPLAY DEVICE INCLUDING THE HETEROCYCLIC COMPOUND | DDT, DRD1, HTR3D | IDO1 1326/4885PDPK1 1213/4885CYP11B2 803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.