Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2949445 | 0.82 | CA9 (0.50) | MAOBCA3CA6CA5ACA9 | |
| SCHEMBL29759451 | 0.77 | ACMSD (0.66) | MAOBCA9CA14ALDH1A1KDM4E | |
| SCHEMBL130520 | 0.77 | ACMSD (0.66) | MAOBCA9CA14ALDH1A1KDM4E | |
| SCHEMBL6715407 | 0.76 | CA12 (0.60) | MAOBCA9CA14ALDH1A1KDM4E | |
| SCHEMBL27405095 | 0.76 | ACMSD (0.64) | MAOBCA9CA14ALDH1A1KDM4E | |
| SCHEMBL10512115 | 0.75 | AR (0.42) | MAOBCA3CA6CA5ACA9 | |
| SCHEMBL9587458 | 0.74 | CES2 (0.58) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL11449961 | 0.73 | ERN1 (0.42) | CA9CA14ALDH1A1KDM4EMEN1 | |
| SCHEMBL6401692 | 0.73 | CA1 (0.63) | MAOBALDH1A1MEN1USP2CA1 | |
| SCHEMBL3187690 | 0.73 | CSNK2A1 (0.63) | ALDH1A1KDM4EMEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109899-A1 | BENZOFURAN COMPOUNDS AS STING AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-04-04 | — | — | US | disclosed |
| US-20050119237-A1 | Non-malignant disease treatment with Ras antagonists | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 2005-06-02 | — | — | US | disclosed |
| EP-1187605-A4 | NON-MALIGNANT DISEASE TREATMENT WITH RAS ANTAGONISTS | THYREOS CORP (US) | 2004-05-26 | — | — | EP | disclosed |
| US-6462086-B1 | SUCH AS FARNESYLTHIOSALICYLIC ACID; INHIBITING PROLIFERATION OF T-CELLS; DIABETES, LUPUS, MULTIPLE SCLEROSIS; GRAFT REJECTION INDUCED BY FOREIGN ANTIGENS; CIRRHOSIS, RESTENOSIS | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) | 2002-10-08 | — | — | US | disclosed |
| EP-1187605-A1 | NON-MALIGNANT DISEASE TREATMENT WITH RAS ANTAGONISTS | Thyreos Corporation (US) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000078303-A1 | NON-MALIGNANT DISEASE TREATMENT WITH RAS ANTAGONISTS | THYREOS CORPORATION (US) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119237-A1 | Non-malignant disease treatment with Ras antagonists | RSU1, KSR1, KRAS | MAOB 3398/4885CA3 4458/4885CA6 4075/4885 |
| US-20240109899-A1 | BENZOFURAN COMPOUNDS AS STING AGONISTS | STING1, MAVS, IRF3 | MAOB 1849/4885CA3 4885/4885CA6 4691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.