Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014640 | 0.85 | KEAP1 (0.57) | KEAP1ALDH1A1SMN1; SMN2POLBKIF11 | |
| SCHEMBL698855 | 0.82 | KEAP1 (0.70) | KEAP1ALDH1A1SMN1; SMN2POLBKIF11 | |
| SCHEMBL1765247 | 0.81 | CA2 (0.63) | KEAP1ALDH1A1SMN1; SMN2POLBCA2 | |
| SCHEMBL1765244 | 0.81 | KEAP1 (0.53) | KEAP1ALDH1A1SMN1; SMN2POLBKIF11 | |
| SCHEMBL12110073 | 0.81 | ALDH1A1 (0.57) | KEAP1ALDH1A1SMN1; SMN2POLBKIF11 | |
| SCHEMBL29899154 | 0.81 | CA2 (0.63) | KEAP1ALDH1A1SMN1; SMN2POLBCA2 | |
| SCHEMBL19220609 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HSD17B10TDP1CYP19A1 | |
| SCHEMBL28015252 | 0.80 | KEAP1 (0.62) | KEAP1ALDH1A1SMN1; SMN2POLBNR3C1 | |
| SCHEMBL14414987 | 0.77 | POLB (0.50) | KEAP1ALDH1A1SMN1; SMN2POLBKIF11 | |
| SCHEMBL2317675 | 0.77 | PTGS1 (0.57) | KEAP1ALDH1A1SMN1; SMN2POLBKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130251-A1 | Reagent for determination of hydrogen peroxide | KYOWA MEDEX CO., LTD. (JP) | 2005-06-16 | — | — | US | disclosed |
| EP-1424554-A1 | REAGENT FOR DETERMINING HYDROGEN PEROXIDE | KYOWA MEDEX CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |