Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.63 |
| ▸ | CA1 | P00915 | 11/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29899154 | 1.00 | CA2 (0.63) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL28014640 | 0.85 | KEAP1 (0.57) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL698855 | 0.82 | KEAP1 (0.70) | KEAP1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL12110073 | 0.81 | ALDH1A1 (0.57) | KEAP1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL1765244 | 0.81 | KEAP1 (0.53) | CA2CA1CA12CA9KEAP1 | |
| SCHEMBL6400945 | 0.81 | KEAP1 (0.53) | CA2CA1CA12CA9KEAP1 | |
| SCHEMBL8349259 | 0.81 | CA2 (0.61) | CA2CA1CA12CA9MAPT | |
| SCHEMBL29932745 | 0.81 | CA2 (0.61) | CA2CA1CA12CA9MAPT | |
| SCHEMBL2308296 | 0.80 | CA2 (0.79) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL28015252 | 0.80 | KEAP1 (0.62) | MEN1KMT2AKEAP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1772493-B1 | AZO DYE | FUJIFILM CORP (JP) | 2016-07-20 | — | — | EP | disclosed |
| US-8546420-B2 | 4, 5-ring annulated indole derivatives for treating or preventing of HCV and related viral infections | MERCK SHARP & DOHME CORP. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20110130552-A1 | AZO DYE | FUJIFILM CORPORATION (JP) | 2011-06-02 | — | — | US | disclosed |
| US-20110124849-A1 | AZO DYE | FUJIFILM CORPORATION (JP) | 2011-05-26 | — | — | US | disclosed |
| US-7947815-B2 | Diazenyl isothiazolo[3,4-B]pyridines as dyes | FUJIFILM CORPORATION (JP) | 2011-05-24 | — | — | US | disclosed |
| US-20100196319-A1 | 4, 5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-08-05 | — | — | US | disclosed |
| US-7651538-B2 | 2-(cyano-),4-((6-methyl-),(7-(cyano-)isothiazolo(4,3-c)pyrid-3-yl)-azo-)phenol; vividcoloring; stability; radiation resistance; shampoo and sweat resistances; friction resistance; heat resistance; alkali resistance; oxidation color dyes; direct dyes; monoazo dyes | KAO CORPORATION (JP) | 2010-01-26 | — | — | US | disclosed |
| EP-2064181-A1 | 4, 5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20090056038-A1 | 2-(cyano-),4-((6-methyl-),(7-(cyano-)isothiazolo(4,3-c)pyrid-3-yl)-azo-)phenol; vividcoloring; stability; radiation resistance; shampoo and sweat resistances; friction resistance; heat resistance; alkali resistance; oxidation color dyes; direct dyes; monoazo dyes | KAO CORPORATION (JP) | 2009-03-05 | — | — | US | disclosed |
| WO-2008082488-A1 | 4, 5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2008-07-10 | — | — | WO | disclosed |
| US-20080027221-A1 | Azo Dye | FUJIFILM CORPORATION (JP) | 2008-01-31 | — | — | US | disclosed |
| EP-1849454-A1 | HAIR DYE COMPOSITION | Kao Corporation (JP) | 2007-10-31 | — | — | EP | disclosed |
| EP-1772493-A1 | AZO DYE | Fujifilm Corporation (JP) | 2007-04-11 | — | — | EP | disclosed |
| US-20050130251-A1 | Reagent for determination of hydrogen peroxide | KYOWA MEDEX CO., LTD. (JP) | 2005-06-16 | — | — | US | disclosed |
| EP-1424554-A1 | REAGENT FOR DETERMINING HYDROGEN PEROXIDE | KYOWA MEDEX CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
| US-6124084-A | AZO DYES; GOOD FASTNESS TO COLOR, HUMIDITY AND HEAT | FUJI PHOTO FILM CO., LTD. (JP) | 2000-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100196319-A1 | 4, 5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS | ZC3HAV1, IDO1, ZC3HAV1L | CA2 4827/4885CA1 4717/4885CA12 4413/4885 |
| US-20090056038-A1 | 2-(cyano-),4-((6-methyl-),(7-(cyano-)isothiazolo(4,3-c)pyrid-3-yl)-azo-)phenol; vividcoloring; stability; radiation resistance; shampoo and sweat resistances; friction resistance; heat resistance; alkali resistance; oxidation color dyes; direct dyes; monoazo dyes | SCO2, IK, AR | CA2 868/4885CA1 1958/4885CA12 2505/4885 |
| US-20080027221-A1 | Azo Dye | IK, ACMSD, ARG1 | CA2 351/4885CA1 680/4885CA12 700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.