SCHEMBL28015252

SCHEMBL28015252

CS(=O)(=O)Nc1cccc(S(=O)(=O)c2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.62
ALDH1A1 P00352 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
NR3C1 P04150 1/20 0.51
HTR6 P50406 2/20 0.50
NAMPT P43490 1/20 0.50
POLB P06746 1/20 0.49
LMNA P02545 1/20 0.49
NR3C2 P08235 1/20 0.49
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PGR P06401 1/20 0.46
USP2 O75604 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28014640 0.94 KEAP1 (0.57) KEAP1ALDH1A1SMN1; SMN2NR3C1NAMPT
SCHEMBL8026965 0.83 KEAP1 (0.69) KEAP1ALDH1A1SMN1; SMN2HTR6LMNA
SCHEMBL13169865 0.81 HTR6 (0.54) KEAP1ALDH1A1SMN1; SMN2HTR6POLB
SCHEMBL698855 0.80 KEAP1 (0.70) KEAP1ALDH1A1SMN1; SMN2NR3C1POLB
SCHEMBL1765247 0.80 CA2 (0.63) KEAP1ALDH1A1SMN1; SMN2POLBMEN1
SCHEMBL29899154 0.80 CA2 (0.63) KEAP1ALDH1A1SMN1; SMN2POLBMEN1
SCHEMBL1765244 0.80 KEAP1 (0.53) KEAP1ALDH1A1SMN1; SMN2NR3C1POLB
SCHEMBL6400945 0.80 KEAP1 (0.53) KEAP1ALDH1A1SMN1; SMN2NR3C1POLB
SCHEMBL12110073 0.80 ALDH1A1 (0.57) KEAP1ALDH1A1SMN1; SMN2NR3C1POLB
SCHEMBL56693 0.78 KEAP1 (1.00) KEAP1ALDH1A1SMN1; SMN2LMNANR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104769021-B Flexible device substrate, flexible device and its manufacture method, laminate and its manufacture method and resin combination 旭化成株式会社 2017-10-10 CN disclosed
CN-104769021-A Substrate for flexible device, flexible device and method for producing same, laminate and method for producing same, and resin composition ASAHI KASEI E MATERIALS CORP 2015-07-08 CN disclosed