SCHEMBL6401017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6401015	1.00	POLB (0.46)	POLBMEN1KMT2ARXFP1P2RX7
	SCHEMBL6403118	0.78	MEN1 (0.54)	POLBMEN1KMT2AP2RX7USP2
	SCHEMBL10859020	0.75	MEN1 (0.63)	POLBMEN1KMT2ARXFP1ALDH1A1
	SCHEMBL4821314	0.73	MEN1 (0.60)	POLBMEN1KMT2ARXFP1ALDH1A1
	SCHEMBL6400980	0.72	SIGMAR1 (0.58)	POLBMEN1KMT2AALDH1A1SIGMAR1
	SCHEMBL6400976	0.72	SIGMAR1 (0.58)	POLBMEN1KMT2AALDH1A1SIGMAR1
	SCHEMBL6402205	0.72	ALDH1A1 (0.49)	MEN1KMT2AALDH1A1HTTSMN1; SMN2
	SCHEMBL24597669	0.72	POLB (0.51)	POLBMEN1KMT2ARXFP1ALDH1A1
	SCHEMBL29258911	0.71	GRIN2D (0.38)	POLBMEN1KMT2ARXFP1P2RX7
	SCHEMBL6400987	0.71	P2RX7 (0.37)	POLBMEN1KMT2AP2RX7SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.