Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | PTPRG | P23470 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403175 | 0.90 | L3MBTL1 (0.45) | PTPRCPTPN2PTPN1PTPRBPTPRG | |
| SCHEMBL6409447 | 0.83 | ALDH1A1 (0.45) | HPGDNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL6403266 | 0.79 | L3MBTL1 (0.43) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL6401373 | 0.79 | MMP3 (0.40) | L3MBTL1ALDH1A1LIMK2 | |
| SCHEMBL946899 | 0.76 | RXRA (0.43) | TRPV1HSD17B10HDAC3HDAC1HDAC2 | |
| SCHEMBL7134738 | 0.75 | CASP1 (0.40) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL6400630 | 0.75 | L3MBTL1 (0.47) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL1844315 | 0.74 | L3MBTL1 (0.46) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL7983925 | 0.74 | L3MBTL1 (0.46) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL6407052 | 0.74 | HDAC3 (0.42) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900237-B2 | Sulfonamide compounds as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-20030158231-A1 | Sulfonamide compounds as protease inhibitors | Celera Corporation | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158231-A1 | Sulfonamide compounds as protease inhibitors | PRSS1, PRSS3, SPINT2 | TRPV1 716/4885ADRB2 4792/4885ADRB1 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.