Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HINT1 | P49773 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1582852 | 0.89 | KDM4E (0.43) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL6401802 | 0.87 | KDM4E (0.41) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL6398833 | 0.86 | HINT1 (0.39) | TAS1R3TAS1R1ALDH1A1MEN1KMT2A | |
| SCHEMBL6399140 | 0.78 | PRMT6 (0.40) | — | |
| SCHEMBL6402956 | 0.77 | KDM4E (0.55) | KDM4ETAS1R3TAS1R1ALDH1A1HINT1 | |
| SCHEMBL6402954 | 0.77 | KDM4E (0.55) | KDM4ETAS1R3TAS1R1ALDH1A1HINT1 | |
| SCHEMBL6398232 | 0.74 | DUT (0.35) | — | |
| SCHEMBL23243909 | 0.72 | KDM4E (0.48) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL27174759 | 0.71 | MEN1 (0.41) | KDM4ETAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL1582222 | 0.71 | STING1 (0.41) | TAS1R3TAS1R1HINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911518-B2 | Polyhedral oligomeric -silsesquioxanes, -silicates and -siloxanes bearing ring-strained olefinic functionalities | HYBRID PLASTICS, LLC (US) | 2005-06-28 | — | — | US | disclosed |
| US-20040068075-A1 | POLYHEDRAL OLIGOMERIC -SILSESQUIOXANES, -SILICATES AND -SILOXANES BEARING RING-STRAINED OLEFINIC FUNCTIONALITIES | HYBRID PLASTICS | 2004-04-08 | — | — | US | disclosed |