Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4963772 | 0.86 | TRPA1 (0.53) | TRPA1ALDH1A1SMN1; SMN2AVPR1AKCNH2 | |
| SCHEMBL6405987 | 0.80 | AVPR1A (0.53) | TRPA1ALDH1A1SMN1; SMN2AVPR1AKCNH2 | |
| SCHEMBL6407406 | 0.79 | CYP3A4 (0.47) | TRPA1ALDH1A1SMN1; SMN2AVPR1AKCNH2 | |
| SCHEMBL6405792 | 0.79 | ALDH1A1 (0.46) | TRPA1ALDH1A1SMN1; SMN2AVPR1AKCNH2 | |
| SCHEMBL6405795 | 0.79 | ALDH1A1 (0.46) | TRPA1ALDH1A1SMN1; SMN2AVPR1AKCNH2 | |
| SCHEMBL5049115 | 0.76 | AVPR1A (0.57) | TRPA1ALDH1A1SMN1; SMN2AVPR1AKCNH2 | |
| SCHEMBL6405064 | 0.76 | AVPR1A (0.49) | TRPA1ALDH1A1SMN1; SMN2AVPR1AKCNH2 | |
| SCHEMBL4962344 | 0.75 | LMNA (0.56) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6412108 | 0.74 | FPR3 (0.46) | ALDH1A1CYP3A4CYP2C9CYP2C19FPR3 | |
| SCHEMBL3136472 | 0.74 | CNR1 (0.45) | AVPR1ANOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2005-12-29 | — | — | US | claimed |
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | TRPA1 4470/4885ALDH1A1 345/4885SMN1; SMN2 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.