Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | HPGD | P15428 | 2/20 | 0.80 |
| ▸ | NPC1 | O15118 | 5/20 | 0.77 |
| ▸ | RAB9A | P51151 | 5/20 | 0.77 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297310 | 0.89 | SMN1; SMN2 (0.68) | PKMSMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL11024162 | 0.87 | RAB9A (1.00) | PKMSMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL7713793 | 0.85 | ALOX5 (0.73) | PKMSMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL6962971 | 0.84 | SMN1; SMN2 (0.89) | PKMSMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL10160183 | 0.83 | SMN1; SMN2 (0.85) | PKMSMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL2216336 | 0.83 | LMNA (0.66) | PKMSMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL31190263 | 0.82 | CA1 (0.60) | PKMSMN1; SMN2ALDH1A1HPGDNPC1 | |
| Nitric Acid SCHEMBL18329349 | 0.82 | RAB9A (0.76) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11839067 | 0.80 | CYP1A2 (0.63) | PKMSMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL6967304 | 0.80 | ALDH1A1 (0.93) | PKMSMN1; SMN2ALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112191238-B | (S) -BIONL derivative CSP filler and preparation method and application thereof | 昆明医科大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-112191238-B | (S) -BIONL derivative CSP filler and preparation method and application thereof | 昆明医科大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-111992196-B | (R) -BIONL derivative CSP filler and preparation method and application thereof | 昆明医科大学 | 2021-05-18 | — | — | CN | disclosed |
| CN-111992196-B | (R) -BIONL derivative CSP filler and preparation method and application thereof | 昆明医科大学 | 2021-05-18 | — | — | CN | disclosed |
| CN-112191238-A | (S) -BIONL derivative CSP filler and preparation method and application thereof | 昆明医科大学 | 2021-01-08 | — | — | CN | disclosed |
| CN-112191238-A | (S) -BIONL derivative CSP filler and preparation method and application thereof | 昆明医科大学 | 2021-01-08 | — | — | CN | disclosed |
| CN-111992196-A | (R) -BIONL derivative CSP filler and preparation method and application thereof | 昆明医科大学 | 2020-11-27 | — | — | CN | disclosed |
| CN-111992196-A | (R) -BIONL derivative CSP filler and preparation method and application thereof | 昆明医科大学 | 2020-11-27 | — | — | CN | disclosed |
| EP-2731956-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | Centre National de la Recherche Scientifique (C.N.R.S.) (FR) | 2014-05-21 | — | — | EP | disclosed |
| WO-2013007724-A1 | P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-01-17 | — | — | WO | disclosed |
| WO-2009094457-A2 | SUBSTITUTED BENZHYDRYLETHERS | AUSPEX PHARMACEUTICALS (US) | 2009-07-30 | — | — | WO | disclosed |
| WO-2008151179-A2 | SUBSTITUTED PHENETHYLAMINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-12-11 | — | — | WO | disclosed |
| EP-0787116-A1 | PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE | Akzo Nobel N.V. (NL) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996011894-A1 | PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE | AKZO NOBEL N.V. (NL) | 1996-04-25 | — | — | WO | disclosed |
| EP-0663897-A1 | PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE. | AKZO NOBEL NV (NL) | 1995-07-26 | — | — | EP | disclosed |
| US-5338454-A | Chiral mobile phase additive having opposite chirality as chiral stationary phase | SUPELCO, INCORPORATED (US) | 1994-08-16 | — | — | US | disclosed |
| WO-1994007814-A1 | PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE | AKZO NOBEL N.V. (NL) | 1994-04-14 | — | — | WO | disclosed |
| EP-0108813-A1 | GRAFTED CHROMATOGRAPHIC FILLER AND METHOD FOR ANALYZING ENANTIOMER MIXTURE USING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-23 | — | — | EP | disclosed |
| EP-0105745-A2 | Packing materials for chromatographic use and their employment in analysing enantiomeric mixtures | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-04-18 | — | — | EP | disclosed |