Sugi Predict

Sugi Predict / Compounds / SCHEMBL6415006

SCHEMBL6415006

SCHEMBL6415006

O=C(O)c1ccc(F)c(F)c1I

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 3/20 0.50
▸ CES1 P23141 3/20 0.50
▸ MAP2K1 Q02750 4/20 0.49
▸ MAP2K2 P36507 2/20 0.49
▸ CYP1A2 P05177 1/20 0.42
▸ ALB P02768 1/20 0.41
▸ BCHE P06276 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ ASPH Q12797 1/20 0.38
▸ KDM8 Q8N371 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ CASP1 P29466 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ TTR P02766 1/20 0.36
▸ SELL P14151 1/20 0.35
▸ SELP P16109 1/20 0.35
▸ WDR5 P61964 1/20 0.35
▸ KEAP1 Q14145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7368860 0.83 MAP2K1 (0.45) CES2CES1MAP2K1MAP2K2CYP1A2
SCHEMBL241797 0.79 CES2 (0.70) CES2CES1MAP2K1MAP2K2CYP1A2
SCHEMBL31454517 0.79 ALDH1A1 (0.44) MAP2K1CYP1A2KDM4ETSHRCASP1
SCHEMBL16277449 0.79 HPGD (0.42) MAP2K1MAP2K2CYP1A2KDM4EASPH
SCHEMBL16277526 0.79 MAP2K1 (0.40) CES2CES1MAP2K1MAP2K2CYP1A2
SCHEMBL3808402 0.78 CYP1A2 (0.58) CYP1A2KDM4ETSHRCASP1SMN1; SMN2
Hydrochloric Acid SCHEMBL4730575 0.77 CES2 (0.67) CES2CES1MAP2K1MAP2K2CYP1A2
SCHEMBL5301076 0.77 CES2 (0.67) CES2CES1MAP2K1MAP2K2CYP1A2
SCHEMBL6718922 0.77 CES2 (0.67) CES2CES1MAP2K1MAP2K2CYP1A2
SCHEMBL1922498 0.76 ALB (0.57) CES2CES1MAP2K1MAP2K2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250314962-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-10-09 — — US disclosed
EP-3971191-A1 BORON-CONTAINING SMALL MOLECULES Bill And Melinda Gates Foundation (US) 2022-03-23 — — EP disclosed
CN-113563368-A Boron-containing small molecules 比尔及梅琳达盖茨基金会 2021-10-29 — — CN disclosed
CN-113321672-A Boron-containing small molecules 比尔及梅琳达盖茨基金会 2021-08-31 — — CN disclosed
EP-3423065-B1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS INC (US) 2021-07-21 — — EP disclosed
CN-109195608-B Boron-containing small molecules 比尔及梅琳达盖茨基金会 2021-05-11 — — CN disclosed
US-10919916-B2 Boron-containing small molecules BILL & MELINDA GATES FOUNDATION (US) 2021-02-16 — — US disclosed
US-20200247827-A1 BORON-CONTAINING SMALL MOLECULES BILL & MELINDA GATES FOUNDATION (US) 2020-08-06 — — US disclosed
US-10611780-B2 Boron-containing small molecules BILL AND MELINDA GATES FOUNDATION (US) 2020-04-07 — — US disclosed
US-20190077814-A1 BORON-CONTAINING SMALL MOLECULES GATES FOUNDATION 2019-03-14 — — US disclosed
EP-3423065-A1 BORON-CONTAINING SMALL MOLECULES Anacor Pharmaceuticals, Inc. (US) 2019-01-09 — — EP disclosed
EP-1359917-B1 THIOXAZINOQUINOLONES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS PHARMACIA & UPJOHN CO LLC (US) 2005-06-29 — — EP disclosed
US-6821969-B2 FOR THERAPY AND PROPHYLAXIS OF HERPESVIRAL INFECTION PHARMACIA & UPJOHN COMPANY 2004-11-23 — — US disclosed
EP-1359917-A1 THIOXAZINOQUINOLONES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS PHARMACIA & UPJOHN COMPANY (US) 2003-11-12 — — EP disclosed
EP-1220858-B1 OXAZINOQUINOLONES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS UPJOHN CO (US) 2003-11-05 — — EP disclosed
US-20020143013-A1 Thioxazinoquinolones as antiviral agents PHARMACIA & UPJOHN COMPANY 2002-10-03 — — US disclosed
WO-2002064145-A1 THIOXAZINOQUINOLONES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS PHARMACIA & UPJOHN COMPANY (US) 2002-08-22 — — WO disclosed
EP-1220858-A2 OXAZINOQUINOLONES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS PHARMACIA & UPJOHN COMPANY (US) 2002-07-10 — — EP disclosed
US-6340680-B1 AS ANTIVIRAL AGENTS, AGAINST VIRUSES OF HERPES FAMILY PHARMACIA AND UPJOHN COMPANY 2002-01-22 — — US disclosed
WO-2001025239-A2 OXAZINOQUINOLONES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS PHARMACIA & UPJOHN COMPANY (US) 2001-04-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190077814-A1 BORON-CONTAINING SMALL MOLECULES BCL6B, BLVRB, BTD CES2 1149/4885CES1 3124/4885MAP2K1 3532/4885
US-20250314962-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS ETV6, RUVBL1, RUVBL2 CES2 2092/4885CES1 3572/4885MAP2K1 1800/4885
US-10919916-B2 Boron-containing small molecules BCL6B, BLVRB, BTD CES2 1149/4885CES1 3124/4885MAP2K1 3532/4885
US-10611780-B2 Boron-containing small molecules BCL6B, BLVRB, BTD CES2 1149/4885CES1 3124/4885MAP2K1 3532/4885
US-20200247827-A1 BORON-CONTAINING SMALL MOLECULES BCL6B, BLVRB, BTD CES2 1149/4885CES1 3124/4885MAP2K1 3532/4885
US-20020143013-A1 Thioxazinoquinolones as antiviral agents DDX5, IRF3, ZC3HAV1 CES2 2411/4885CES1 1005/4885MAP2K1 4605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.