Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887143 | 0.94 | PTGS2 (0.35) | HPGDMEN1KMT2A | |
| SCHEMBL5887155 | 0.87 | NOTUM (0.36) | ALOX5 | |
| SCHEMBL6047579 | 0.85 | GRIA1 (0.31) | — | |
| SCHEMBL5887199 | 0.85 | KMT2A (0.35) | HPGDMEN1KMT2ATP53 | |
| SCHEMBL5887288 | 0.85 | ALDH1A3 (0.41) | — | |
| SCHEMBL5887320 | 0.85 | ACHE (0.33) | HPGDKMT2AALOX5 | |
| SCHEMBL5887625 | 0.84 | HSP90AA1 (0.36) | MEN1KMT2AHSP90AA1HSP90AB1TP53 | |
| SCHEMBL5887667 | 0.83 | NPC1 (0.39) | HPGDMEN1KMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL5887653 | 0.83 | FFAR2 (0.40) | KMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL5887589 | 0.82 | APEX1 (0.36) | HSP90AA1HSP90AB1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026903-A1 | CCK-1 receptor modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026903-A1 | CCK-1 receptor modulators | CCKAR, CCKBR, GLP1R | HPGD 1666/4885MEN1 2294/4885KMT2A 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.