SCHEMBL641809

SCHEMBL641809

COC(=O)N(C)[C@@H](C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.34
TP53 P04637 1/20 0.33
NPY5R Q15761 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000970 1.00 LTA4H (0.34) LTA4HTP53NPY5RSMN1; SMN2
SCHEMBL13033875 0.81 ALDH1A1 (0.35) NPY5RSMN1; SMN2
SCHEMBL8386456 0.79 CHRNB2 (0.31)
SCHEMBL8386454 0.79
SCHEMBL2736118 0.79
SCHEMBL1983612 0.77 ADAMTS4 (0.33) TP53SMN1; SMN2
SCHEMBL755790 0.77 ADAMTS4 (0.33) TP53SMN1; SMN2
SCHEMBL6016722 0.77 TGFBR1 (0.34) LTA4HTP53
SCHEMBL6016723 0.77 TGFBR1 (0.34) LTA4HTP53
SCHEMBL3636117 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152680-B1 METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE SANOFI SA (FR) 2015-06-24 EP disclosed
US-20120215007-A1 METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE SANOFI (FR) 2012-08-23 US disclosed
US-20120215007-A1 METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE SANOFI (FR) 2012-08-23 US disclosed
US-20120215007-A1 METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE SANOFI (FR) 2012-08-23 US disclosed
US-8119813-B2 Method for preparing enantiomerically enriched N-carboxyanhydride SANOFI-AVENTIS (FR) 2012-02-21 US disclosed
US-8119813-B2 Method for preparing enantiomerically enriched N-carboxyanhydride SANOFI-AVENTIS (FR) 2012-02-21 US disclosed
US-8119813-B2 Method for preparing enantiomerically enriched N-carboxyanhydride SANOFI-AVENTIS (FR) 2012-02-21 US disclosed
WO-2011091532-A1 HEPATITIS C INHIBITOR COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-08-04 WO disclosed
US-20100113797-A1 METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE SANOFI-AVENTIS (FR) 2010-05-06 US disclosed
US-20100113797-A1 METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE SANOFI-AVENTIS (FR) 2010-05-06 US disclosed
US-20100113797-A1 METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE SANOFI-AVENTIS (FR) 2010-05-06 US disclosed
WO-2009004141-A2 METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE SANOFI-AVENTIS (FR) 2009-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120215007-A1 METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE DNPEP, NPPA, CPN1 LTA4H 2882/4885TP53 2364/4885NPY5R 511/4885
US-20100113797-A1 METHOD FOR PREPARING ENANTIOMERICALLY ENRICHED N-CARBOXYANHYDRIDE DNPEP, NPPA, CPN1 LTA4H 2882/4885TP53 2364/4885NPY5R 511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.