Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239955 | 0.70 | ALDH1A1 (0.34) | CYP2C9MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL6418205 | 0.64 | PDE8B (0.37) | PDE8BCYP2C9MEN1KMT2ATP53 | |
| SCHEMBL3340212 | 0.64 | ALDH1A1 (0.33) | PDE8BCYP2C9MEN1KMT2AHSD17B10 | |
| SCHEMBL3342926 | 0.64 | ALDH1A1 (0.33) | PDE8BCYP2C9MEN1KMT2AHSD17B10 | |
| SCHEMBL3341702 | 0.64 | ALDH1A1 (0.33) | PDE8BCYP2C9MEN1KMT2AHSD17B10 | |
| SCHEMBL30515668 | 0.62 | ALDH1A1 (0.37) | CYP2C9MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL3340214 | 0.61 | ALDH1A1 (0.33) | CYP2C9MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL3341705 | 0.61 | ALDH1A1 (0.33) | CYP2C9MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL3342929 | 0.61 | ALDH1A1 (0.33) | CYP2C9MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL28066962 | 0.58 | PDE8B (0.40) | PDE8BCYP2C9MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038047-A1 | Azaquinazoline derivatives | EDWARDS PAUL JOHN (GB) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038047-A1 | Azaquinazoline derivatives | AZI2, P2RX5, P2RX7 | PDE8B 36/4885CYP2C9 429/4885MEN1 4259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.