Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL187320 | 1.00 | — | — | |
| Glycerin SCHEMBL27645554 | 1.00 | LMNA (0.90) | LMNAALDH1A1THRBTDP1OR51E2 | |
| Glycerin SCHEMBL28633505 | 1.00 | — | — | |
| Glycerin SCHEMBL8850244 | 1.00 | — | — | |
| Glycerin SCHEMBL17072161 | 0.95 | LMNA (0.82) | LMNAALDH1A1THRBTDP1OR51E2 | |
| Glycerin SCHEMBL27788548 | 0.95 | — | — | |
| Glycerin SCHEMBL28738391 | 0.95 | — | — | |
| Glycerin SCHEMBL28590439 | 0.95 | — | — | |
| Glycerin SCHEMBL27421408 | 0.95 | — | — | |
| Glycerin SCHEMBL28007766 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349816-B | Water-based ink, print cartridge, ink setting system and method, recording device and method | 富士施乐株式会社 | 2019-08-02 | — | — | CN | disclosed |
| US-20050171367-A1 | Method for manufacturing a combined fatty acid / lecithin ruminally protected feed supplement. | DeLoach, Terry (US) | 2005-08-04 | — | — | US | disclosed |
| EP-1175154-B1 | METHOD FOR MANUFACTURING RUMEN BYPASS FEED SUPPLEMENT | NOREL ACQUISITION CORP (US) | 2005-02-09 | — | — | EP | disclosed |
| EP-1175154-A4 | METHOD FOR MANUFACTURING RUMEN BYPASS FEED SUPPLEMENT | NOREL ACQUISITION CORP (US) | 2003-01-22 | — | — | EP | disclosed |
| EP-1175154-A1 | METHOD FOR MANUFACTURING RUMEN BYPASS FEED SUPPLEMENT | Norel Acquisition Corp. (US) | 2002-01-30 | — | — | EP | disclosed |
| US-6229031-B1 | Method for manufacturing rumen bypass feed supplements | NOREL AQUISITIONS, INC. | 2001-05-08 | — | — | US | disclosed |
| WO-2000067589-A1 | METHOD FOR MANUFACTURING RUMEN BYPASS FEED SUPPLEMENT | NOREL ACQUISITION CORP. (US) | 2000-11-16 | — | — | WO | disclosed |