Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6423522 | 0.83 | PDK2 (0.39) | PDK2P2RX7PTGDR2 | |
| SCHEMBL6420064 | 0.80 | GRIN2B (0.38) | PDK2GAAALDH1A1KDM4EP2RX7 | |
| SCHEMBL6419465 | 0.79 | PDK2 (0.36) | PDK2P2RX7PTGDR2CHRM2CHRM4 | |
| SCHEMBL6422824 | 0.78 | CHRM5 (0.41) | PDK2GAAALDH1A1P2RX7PTGDR2 | |
| SCHEMBL6422607 | 0.78 | P2RX7 (0.43) | PDK2ALDH1A1P2RX7PTGDR2 | |
| SCHEMBL6422956 | 0.77 | CHRM5 (0.42) | ALDH1A1KDM4ECHRM5CHRM1 | |
| SCHEMBL6420512 | 0.76 | GRIN2B (0.40) | ALDH1A1CHRM5CHRM1 | |
| SCHEMBL6423885 | 0.76 | PTGDR2 (0.37) | PDK2P2RX7PTGDR2 | |
| SCHEMBL6423530 | 0.76 | PTGDR2 (0.36) | PDK2ALDH1A1P2RX7PTGDR2 | |
| SCHEMBL6420047 | 0.76 | PTGDR2 (0.37) | PDK2P2RX7PTGDR2CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |
| EP-1173438-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063208-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |