Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419294 | 0.83 | PDK2 (0.37) | PDK2P2RX7PTGDR2 | |
| SCHEMBL6420064 | 0.78 | GRIN2B (0.38) | PDK2P2RX7GRIN2BPTGDR2MEN1 | |
| SCHEMBL6423530 | 0.76 | PTGDR2 (0.36) | PDK2P2RX7GRIN2BPTGDR2MEN1 | |
| SCHEMBL6422824 | 0.76 | CHRM5 (0.41) | PDK2P2RX7GRIN2BPTGDR2MEN1 | |
| SCHEMBL6422607 | 0.76 | P2RX7 (0.43) | PDK2P2RX7PTGDR2 | |
| SCHEMBL6420249 | 0.76 | PTGDR2 (0.36) | PDK2P2RX7PTGDR2MEN1KMT2A | |
| SCHEMBL6422386 | 0.75 | CD274 (0.42) | — | |
| SCHEMBL6419465 | 0.75 | PDK2 (0.36) | PDK2P2RX7GRIN2BPTGDR2 | |
| SCHEMBL6422956 | 0.75 | CHRM5 (0.42) | MEN1KMT2A | |
| SCHEMBL6420512 | 0.74 | GRIN2B (0.40) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |
| EP-1173438-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063208-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |