Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420631 | 0.87 | PTGDR2 (0.34) | LMNAMAOB | |
| SCHEMBL6422857 | 0.86 | PTGDR2 (0.35) | LMNA | |
| SCHEMBL6420518 | 0.78 | CHRM2 (0.36) | ALDH1A1LMNA | |
| SCHEMBL6419465 | 0.73 | PDK2 (0.36) | POLB | |
| SCHEMBL6419294 | 0.73 | PDK2 (0.37) | ALDH1A1KDM4EGAATSHR | |
| SCHEMBL6423885 | 0.72 | PTGDR2 (0.37) | — | |
| SCHEMBL6420249 | 0.72 | PTGDR2 (0.36) | ALDH1A1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL6422607 | 0.72 | P2RX7 (0.43) | ALDH1A1POLB | |
| SCHEMBL6422824 | 0.70 | CHRM5 (0.41) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL6420512 | 0.70 | GRIN2B (0.40) | ALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |
| EP-1173438-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063208-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |