Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422857 | 0.99 | PTGDR2 (0.35) | PTGDR2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6420518 | 0.89 | CHRM2 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6420533 | 0.87 | ALDH1A1 (0.33) | MAOBLMNA | |
| SCHEMBL6420017 | 0.78 | ALDH1A1 (0.32) | PDK2P2RX7 | |
| SCHEMBL6419465 | 0.77 | PDK2 (0.36) | PTGDR2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6420249 | 0.76 | PTGDR2 (0.36) | PTGDR2PDK2P2RX7LMNA | |
| SCHEMBL6422607 | 0.76 | P2RX7 (0.43) | PTGDR2PDK2P2RX7 | |
| SCHEMBL6419294 | 0.75 | PDK2 (0.37) | PTGDR2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6420512 | 0.74 | GRIN2B (0.40) | CHRM5CHRM1LMNA | |
| SCHEMBL6422824 | 0.74 | CHRM5 (0.41) | PTGDR2CHRM5CHRM1PDK2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |