Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410288 | 0.84 | CYP1A2 (0.38) | CYP1A2CYP2D6MAPK1LMNATRPV1 | |
| SCHEMBL7516559 | 0.75 | CYP1A2 (0.39) | CYP1A2CYP2D6MAPK1LMNATRPV1 | |
| SCHEMBL6418989 | 0.74 | IGF1R (0.50) | BCHEHSP90AA1HSP90AB1CA2ALOX5 | |
| SCHEMBL67859 | 0.73 | LMNA (0.58) | CYP1A2CYP2D6MAPK1LMNATRPV1 | |
| SCHEMBL28228079 | 0.73 | CYP1A2 (0.54) | CYP1A2CYP2D6MAPK1LMNATRPV1 | |
| SCHEMBL28323636 | 0.73 | ACHE (0.41) | CYP1A2CYP2D6MAPK1LMNATRPA1 | |
| SCHEMBL12457245 | 0.73 | TYR (0.50) | CYP1A2CYP2D6MAPK1LMNATRPV1 | |
| SCHEMBL6415462 | 0.72 | BCHE (0.49) | BCHEHSP90AA1HSP90AB1CA2ALOX5 | |
| SCHEMBL6055205 | 0.70 | GABRA1 (0.44) | CYP1A2LMNATRPV1SLC6A2HTR2B | |
| SCHEMBL6417176 | 0.70 | GABRA1 (0.58) | CYP1A2LMNATRPV1TRPA1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277700-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2005-12-15 | — | — | US | disclosed |
| US-20040199028-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | MCNEIL-PPC, INC | 2004-10-07 | — | — | US | disclosed |
| US-20030139478-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HARPER D SCOTT | 2003-07-24 | — | — | US | disclosed |
| WO-2003053897-A1 | NON-HALOGENATED HYDROXYALKYL-SUBSTITUTED PHENOL COMPOUNDS, ANTIMICROBIAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME | WARNER-LAMBERT COMPANY LLC (US) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277700-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | CYP1A2 1390/4885CYP2D6 640/4885MAPK1 3536/4885 |
| US-20030139478-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | CYP1A2 1390/4885CYP2D6 640/4885MAPK1 3536/4885 |
| US-20040199028-A1 | Non-halogenated hydroxyalkyl-substituted phenol compounds, antimicrobial compositions containing the same, and methods of using the same | HDHD5, TYR, NONO | CYP1A2 1390/4885CYP2D6 640/4885MAPK1 3536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.