Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 5/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | FABP6 | P51161 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94362 | 0.79 | KDM4E (0.33) | KDM4EALDH1A1LMNADHFR | |
| SCHEMBL4002943 | 0.77 | CSNK2A2 (0.35) | KDM4EALDH1A1LMNADHFRCSNK2A2 | |
| SCHEMBL6356983 | 0.74 | CHUK (0.36) | KDM4EALDH1A1LMNADHFRCSNK2A2 | |
| SCHEMBL28995610 | 0.72 | MMP12 (0.36) | KDM4EALDH1A1LMNAHSD17B10GLA | |
| SCHEMBL13267125 | 0.70 | KDM4E (0.39) | KDM4EALDH1A1LMNADHFRHSD17B10 | |
| SCHEMBL4239753 | 0.70 | PNP (0.34) | KDM4EALDH1A1LMNACSNK2A2CSNK2B | |
| SCHEMBL2938699 | 0.67 | PDPK1 (0.37) | KDM4EALDH1A1LMNADHFRHSD17B10 | |
| SCHEMBL1980402 | 0.67 | ALDH1A1 (0.37) | KDM4EALDH1A1LMNAHSD17B10GLA | |
| SCHEMBL25272928 | 0.66 | CDK5 (0.51) | KDM4EALDH1A1LMNADHFRMTOR | |
| SCHEMBL21620891 | 0.65 | NOS3 (0.41) | FABP6MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513928-B1 | A BANK OF STEM CELLS FOR PRODUCING CELLS FOR TRANSPLANTATION HAVING HLA ANTIGENS MATCHING THOSE OF TRANSPLANT RECIPIENTS, AND METHODS FOR MAKING AND USING SUCH A STEM CELL BANK | ADVANCED CELL TECH INC (US) | 2019-08-21 | — | — | EP | disclosed |
| US-20190225937-A1 | BANK OF STEM CELLS FOR PRODUCING CELLS FOR TRANSPLANTATION HAVING HLA ANTIGENS MATCHING THOSE OF TRANSPLANT RECIPIENTS AND METHODS FOR MAKING AND USING SUCH A STEM CELL BANK | ADVANCED CELL TECH INC (US) | 2019-07-25 | — | — | US | disclosed |
| US-20130276154-A1 | Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank | ADVANCED CELL TECHNOLOGY, INC. | 2013-10-17 | — | — | US | disclosed |
| EP-1513928-A2 | A BANK OF STEM CELLS FOR PRODUCING CELLS FOR TRANSPLANTATION HAVING HLA ANTIGENS MATCHING THOSE OF TRANSPLANT RECIPIENTS, AND METHODS FOR MAKING AND USING SUCH A STEM CELL BANK | Advanced Cell Technology, Inc. (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20040091936-A1 | Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank | ADVANCED CELL TECHNOLOGY, INC. | 2004-05-13 | — | — | US | disclosed |
| WO-2003100018-A2 | A BANK OF STEM CELLS FOR TRANSPLANTATION | ADVANCED CELL TECHNOLOGY, INC. (US) | 2003-12-04 | — | — | WO | disclosed |