SCHEMBL94362

SCHEMBL94362

Cc1nc(N)nc2[nH]c(S)nc12

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
DHFR P00374 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6424960 0.79 KDM4E (0.34) KDM4EALDH1A1LMNADHFR
SCHEMBL1766002 0.79 ADORA2A (0.33)
SCHEMBL94822 0.76
SCHEMBL9465286 0.72 AKR1B1 (0.31) DHFR
SCHEMBL3916442 0.72 ADORA1 (0.30)
SCHEMBL8216344 0.68 ADORA3 (0.35) ALDH1A1
SCHEMBL1898084 0.68 NUDT1 (0.41) KDM4EALDH1A1LMNA
SCHEMBL2938699 0.64 PDPK1 (0.37) KDM4EALDH1A1LMNADHFR
SCHEMBL159447 0.64 KDM4E (0.53) KDM4EALDH1A1LMNA
SCHEMBL2953678 0.63 ADORA3 (0.38) ALDH1A1DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220273689-A1 POTENTIATION OF ANTIVIRAL NUCLEOBASES AS RNA VIRUS THERAPY REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-09-01 US claimed
WO-2021007283-A1 POTENTIATION OF ANTIVIRAL NUCLEOBASES AS RNA VIRUS THERAPY REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2021-01-14 WO claimed
EP-2177606-A2 N-deoxyribosyltransferases from lactobacillus, corresponding nucleotide sequences and their applications INSTITUT PASTEUR (FR) 2010-04-21 EP claimed
EP-1427819-B1 LACTOBACILLUS N-DEOXYRIBOSYL TRANSFERASES, CORRESPONDING NUCLEOTIDE SEQUENCES AND THEIR USES PASTEUR INSTITUT (FR) 2009-12-23 EP claimed
US-20080280329-A1 Enzymatic synthesis of deoxyribonucleosides TISCHER WILHELM 2008-11-13 US claimed
US-20080250513-A1 LACTOBACILLUS N-DEOXYRIBOSYL TRANSFERASES, CORRESPONDING NUCLEOTIDE SEQUENCES AND THEIR USES INSTITUT PASTEUR (FR) 2008-10-09 US claimed
CN-101217999-A Personal care compositions and methods for the beautification of mammalian skin and hair PROCTER & GAMBLE (US) 2008-07-09 CN claimed
EP-1901817-A2 PERSONAL CARE COMPOSITIONS AND METHODS FOR THE BEAUTIFICATION OF MAMMALIAN SKIN AND HAIR The Procter and Gamble Company (US) 2008-03-26 EP claimed
WO-2007007255-A2 PERSONAL CARE COMPOSITIONS AND METHODS FOR THE BEAUTIFICATION OF MAMMALIAN SKIN AND HAIR THE PROCTER & GAMBLE COMPANY (US) 2007-01-18 WO claimed
US-20070009474-A1 Personal care compositions and methods for the beautification of mammalian skin and hair THE PROCTER & GAMBLE COMPANY 2007-01-11 US claimed
US-20060068473-A1 Lactobacillus N-deoxyribosyl transferases, corresponding nucleotide sequences and their uses INSTITUT PASTEUR (FR) 2006-03-30 US claimed
EP-1206551-A2 ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOSIDES Roche Diagnostics GmbH (DE) 2002-05-22 EP claimed
WO-2001014566-A2 ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOSIDES ROCHE DIAGNOSTICS GMBH (DE) 2001-03-01 WO claimed
US-12583932-B2 CD38 and ICAM1 antibodies and uses thereof VIRTUOSO BINCO, INC. (US) 2026-03-24 US disclosed
EP-2498772-B1 COMPOSITION AND METHODS FOR IMPROVING SKIN APPEARANCE SYTHEON LTD (US) 2025-07-30 EP disclosed
US-12054768-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-06 US disclosed
US-4766110-A INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS RYAN JAMES W (US) 1988-08-23 US disclosed
US-4720459-A Myelomas for producing human/human hybridomas MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) 1988-01-19 US disclosed
EP-0073143-B1 NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES Ryan, James Walter (US) 1985-11-21 EP disclosed
EP-0073143-A2 Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides Ryan, James Walter (US) 1983-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273689-A1 POTENTIATION OF ANTIVIRAL NUCLEOBASES AS RNA VIRUS THERAPY NSUN3, NSUN2, RNMT KDM4E 3366/4885ALDH1A1 2235/4885LMNA 2816/4885
US-12583932-B2 CD38 and ICAM1 antibodies and uses thereof FCGR2A, FCGR3B, FCGR1A KDM4E 3002/4885ALDH1A1 902/4885LMNA 1047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.