Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98574 | 0.97 | — | — | |
| Bromide SCHEMBL11582419 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| Water SCHEMBL6427091 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| Fluoride Ion SCHEMBL6232001 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| Fluoride Ion SCHEMBL946248 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| SCHEMBL2475486 | 0.88 | LMNA (0.33) | TSHRACHELMNAALOX12ALDH1A1 | |
| SCHEMBL31047812 | 0.85 | LMNA (0.32) | TSHRACHELMNAALOX12 | |
| SCHEMBL11518513 | 0.85 | ALDH1A1 (0.35) | TSHRACHELMNAALOX12ALDH1A1 | |
| Perchlorate SCHEMBL3299468 | 0.85 | PTGS2 (0.32) | TSHRACHELMNAALOX12TDP1 | |
| SCHEMBL31047848 | 0.85 | LMNA (0.32) | TSHRACHELMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022145352-A1 | COMPOUND, BONDING AGENT, JOINED BODY, PRINTED SUBSTRATE, AND METHOD FOR MANUFACTURING BONDED BODY | 株式会社ダイセル | 2022-07-07 | — | — | WO | disclosed |
| US-6918662-B2 | Ink composition and inkjet recording method and apparatus using the ink composition | RICOH COMPANY LIMITED (JP) | 2005-07-19 | — | — | US | disclosed |
| US-20040179066-A1 | Ink composition and inkjet recording method and apparatus using the ink composition | RICOH COMPANY LIMITED (JP) | 2004-09-16 | — | — | US | disclosed |
| US-6730149-B2 | COLORANT AND A SOLVENT; ZETA POTENTIAL BETWEEN THE COLORANT AND GLASS, SILICON, SILICON OXIDE, TITANIUM OXIDE, CHROMIUM OXIDE, TITANIUM NITRIDE, SILICON NITRIDE, ZIRCONIUM AND POLYIMIDE IS FROM 0--50 MV AT A PH OF 6.5-11.5 | RICOH COMPANY LIMITED (JP) | 2004-05-04 | — | — | US | disclosed |
| US-20030010252-A1 | Ink composition and inkjet recording method and apparatus using the ink composition | RICOH COMPANY LIMITED (JP) | 2003-01-16 | — | — | US | disclosed |