Fluoride Ion

Fluoride Ion

SCHEMBL6232001

C[S+](C)c1ccccc1.C[S+](C)c1ccccc1.C[S+](C)c1ccccc1.C[S+](C)c1ccccc1.C[S+](C)c1ccccc1.[F-].[F-].[F-].[F-].[F-]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.37
ACHE P22303 2/20 0.37
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
ALDH1A1 P00352 2/20 0.35
NOS3 P29474 2/20 0.32
NOS1 P29475 2/20 0.32
DPP4 P27487 2/20 0.32
CA4 P22748 2/20 0.32
TP53 P04637 1/20 0.32
TAS2R38 P59533 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRK1 P41145 1/20 0.31
OPRL1 P41146 1/20 0.31
APOBEC3A P31941 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride Ion SCHEMBL946248 1.00 TSHR (0.37) TSHRACHELMNAALOX12ALDH1A1
SCHEMBL98574 0.97
Bromide SCHEMBL11582419 0.93 TSHR (0.37) TSHRACHELMNAALOX12ALDH1A1
Hydrochloric Acid SCHEMBL6425322 0.93 TSHR (0.37) TSHRACHELMNAALOX12ALDH1A1
Water SCHEMBL6427091 0.93 TSHR (0.37) TSHRACHELMNAALOX12ALDH1A1
SCHEMBL2475486 0.88 LMNA (0.33) TSHRACHELMNAALOX12ALDH1A1
SCHEMBL11518513 0.85 ALDH1A1 (0.35) TSHRACHELMNAALOX12ALDH1A1
SCHEMBL31047812 0.85 LMNA (0.32) TSHRACHELMNAALOX12
Perchlorate SCHEMBL3299468 0.85 PTGS2 (0.32) TSHRACHELMNAALOX12TDP1
SCHEMBL31047848 0.85 LMNA (0.32) TSHRACHELMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958415-B2 Synthesis of pentafluorosulfuranyl arylenes AIR PRODUCTS AND CHEMICALS, INC. (US) 2005-10-25 US disclosed
EP-1533297-A1 Synthesis of pentafluorosulfuranyl arylenes AIR PRODUCTS AND CHEMICALS, INC. (US) 2005-05-25 EP disclosed
US-20050107632-A1 Synthesis of pentafluorosulfuranyl arylenes AIR PRODUCTS AND CHEMICALS, INC. 2005-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050107632-A1 Synthesis of pentafluorosulfuranyl arylenes TST, DHRS9, HDHD5 TSHR 67/4885ACHE 3168/4885LMNA 4428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.