SCHEMBL6426425

SCHEMBL6426425

O=S(=O)(Cl)c1cccc(OC(F)(F)C(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.41
PIM2 Q9P1W9 1/20 0.41
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
SCN9A Q15858 1/20 0.40
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
EPHX2 P34913 1/20 0.38
SLC40A1 Q9NP59 1/20 0.37
PRKCA P17252 2/20 0.37
KAT6A Q92794 1/20 0.36
MAPT P10636 4/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTT P42858 1/20 0.36
CETP P11597 2/20 0.36
ABL1 P00519 1/20 0.36
BCR P11274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL442910 0.85 SLC40A1 (0.48) ALDH1A1HSD17B10TDP1SLC40A1KAT6A
SCHEMBL113409 0.81 DRD1 (0.44) LMNAPOLBALDH1A1HSD17B10TDP1
SCHEMBL1489401 0.80 TRPV1 (0.40) SCN9AALDH1A1HSD17B10TDP1PTGES2
SCHEMBL498326 0.78 PIM1 (0.48) PIM1PIM2LMNAPOLBEPHX2
SCHEMBL6426423 0.78 PTGES2 (0.42) PIM1PIM2LMNAPOLBSCN9A
SCHEMBL1608200 0.74 PIM1 (0.46) PIM1PIM2LMNAPOLBSCN9A
SCHEMBL10654647 0.74 SCN9A (0.36) PIM1PIM2LMNAPOLBSCN9A
SCHEMBL3923038 0.72 PGR (0.51) TDP1HTTPTGES2
SCHEMBL22374884 0.72 PPARA (0.44) ALDH1A1HSD17B10EPHX2KAT6AMAPT
SCHEMBL18152 0.72 NFE2L2 (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240253023-A1 PERFLUORINATED AMIDE SALTS AND THEIR USES AS IONIC CONDUCTING MATERIALS MICHOT CHRISTOPHE (FR) 2024-08-01 US disclosed
US-20050074668-A1 Perfluorinated amide salts and their uses as ionic conducting materials MICHOT CHRISTOPHE (FR) 2005-04-07 US disclosed
US-20030052310-A1 Perfluorinated amide salts and their uses as ionic conducting materials MICHOT CHRISTOPHE (FR) 2003-03-20 US disclosed
US-20020009650-A1 Perfluorinated amide salts and their uses as ionic conducting materials MICHOT CHRISTOPHE (FR) 2002-01-24 US disclosed
US-6319428-B1 Perfluorinated amide salts and their uses as ionic conducting materials HYDRO-QUEBEC (CA) 2001-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020009650-A1 Perfluorinated amide salts and their uses as ionic conducting materials AFF4, NHERF1, AFF2 PIM1 1688/4885PIM2 1668/4885LMNA 1713/4885
US-20050074668-A1 Perfluorinated amide salts and their uses as ionic conducting materials AFF4, AFF2, AFF1 PIM1 1692/4885PIM2 1735/4885LMNA 949/4885
US-20240253023-A1 PERFLUORINATED AMIDE SALTS AND THEIR USES AS IONIC CONDUCTING MATERIALS AFF4, AFF2, AFF1 PIM1 1834/4885PIM2 2118/4885LMNA 1160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.