Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23293010 | 0.81 | TSHR (0.38) | ALDH1A1TSHRPPARAMEN1CYP1A2 | |
| SCHEMBL14879747 | 0.77 | PPARA (0.36) | ALDH1A1TSHRPPARAMEN1CYP1A2 | |
| SCHEMBL9064823 | 0.77 | TSHR (0.36) | ALDH1A1TSHRPPARACYP2D6CYP2C19 | |
| SCHEMBL23567953 | 0.75 | TSHR (0.42) | ALDH1A1TSHRPPARAMEN1CYP1A2 | |
| SCHEMBL362903 | 0.75 | DGAT1 (0.52) | ALDH1A1TSHRDGAT1CHRM1 | |
| SCHEMBL6863429 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRPPARAMEN1CYP1A2 | |
| SCHEMBL10127306 | 0.73 | RIPK1 (0.34) | ALDH1A1TSHRPPARAMEN1CYP1A2 | |
| SCHEMBL4464867 | 0.72 | GAA (0.44) | ALDH1A1TSHRPPARAMEN1CYP1A2 | |
| SCHEMBL15308350 | 0.72 | ALDH1A1 (0.38) | ALDH1A1TSHRDGAT1 | |
| Hydrochloric Acid SCHEMBL338771 | 0.70 | GAA (0.42) | ALDH1A1TSHRPPARAMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119799-B2 | Method for the production of polyisocyanates comprising isocyanurate groups and use therof | BASF AKTIENGESELLSCHAFT (DE) | 2012-02-21 | — | — | US | claimed |
| US-9428437-B2 | Method for dehydrating alpha-substituted carboxylic acids | EVONIK ROEHM GMBH (DE) | 2016-08-30 | — | — | US | disclosed |
| US-20160090344-A1 | METHOD FOR DEHYDRATING ALPHA-SUBSTITUTED CARBOXYLIC ACIDS | EVONIK ROEHM GMBH (DE) | 2016-03-31 | — | — | US | disclosed |
| US-8119799-B2 | Method for the production of polyisocyanates comprising isocyanurate groups and use therof | BASF AKTIENGESELLSCHAFT (DE) | 2012-02-21 | — | — | US | disclosed |
| US-7993630-B2 | Protection of skin from UV and peroxide | BIODERM RESEARCH (US) | 2011-08-09 | — | — | US | disclosed |
| CN-102076864-A | Recombinant cells producing 2-hydroxyisobutyric acid | EVONIK ROEHM GMBH | 2011-05-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090344-A1 | METHOD FOR DEHYDRATING ALPHA-SUBSTITUTED CARBOXYLIC ACIDS | ALAD, EBP, HSD17B12 | ALDH1A1 122/4885TSHR 4476/4885PPARA 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.