Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428205 | 0.81 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL8806288 | 0.74 | NOS3 (0.36) | CRHR1 | |
| SCHEMBL6430830 | 0.71 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL6428378 | 0.68 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL6430842 | 0.66 | LMNA (0.39) | CRHR1 | |
| SCHEMBL5843305 | 0.66 | CRHR1 (0.76) | CRHR1 | |
| SCHEMBL6430833 | 0.65 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL6428279 | 0.65 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL8344776 | 0.64 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL6430249 | 0.64 | SCN4A (0.33) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900301-B2 | Backbone modified oligonucleotide analogues | ISIS PHARMACEUTICALS, INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |