Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 4/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428405 | 0.87 | HTR1A (0.35) | SCN4ASCN9AATM | |
| SCHEMBL6430830 | 0.80 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL5843648 | 0.74 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL6445881 | 0.73 | PDGFRB (0.36) | CRHR1PDGFRBKDRATM | |
| SCHEMBL6428305 | 0.70 | CRHR1 (0.44) | CRHR1SCN9A | |
| SCHEMBL6430481 | 0.68 | LMNA (0.39) | CRHR1ATM | |
| SCHEMBL5842899 | 0.68 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL6430253 | 0.68 | CRHR1 (0.42) | SCN4ACRHR1SCN9A | |
| SCHEMBL6430364 | 0.68 | CRHR1 (0.39) | SCN4ACRHR1SCN9A | |
| SCHEMBL6450221 | 0.68 | CRHR1 (0.39) | CRHR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |