Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844256 | 0.71 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL5844067 | 0.69 | PDK2 (0.37) | KDM4EPDK2 | |
| SCHEMBL5844251 | 0.69 | L3MBTL1 (0.37) | ALDH1A1POLBTLR8KDM4ENPSR1 | |
| SCHEMBL6429265 | 0.69 | CA2 (0.35) | ALDH1A1POLBMAPTTLR8KDM4E | |
| SCHEMBL12495762 | 0.67 | PDK2 (0.42) | ALDH1A1MAPTTLR8KDM4ENPSR1 | |
| SCHEMBL857094 | 0.64 | CYP1A2 (0.36) | ALDH1A1TLR8KDM4ENPSR1L3MBTL1 | |
| SCHEMBL259365 | 0.61 | SMN1; SMN2 (0.42) | ALDH1A1KDM4ETLR7PDK2 | |
| SCHEMBL11044330 | 0.60 | ADRB2 (0.46) | ALDH1A1POLBMAPTKDM4ENPSR1 | |
| SCHEMBL13975423 | 0.59 | HTR1A (0.46) | ALDH1A1POLBMAPTNPSR1L3MBTL1 | |
| SCHEMBL20840567 | 0.59 | KDM4E (0.34) | ALDH1A1KDM4EPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |