Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | BACE1 | P56817 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3218793 | 0.88 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1BACE1LMNAMAPT | |
| SCHEMBL3200550 | 0.88 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1BACE1MAPTPOLB | |
| SCHEMBL3200647 | 0.86 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1BACE1LMNAMAPT | |
| SCHEMBL5146907 | 0.82 | ALDH1A1 (0.74) | ALDH1A1L3MBTL1BACE1LMNAMAPT | |
| SCHEMBL1219328 | 0.81 | FFAR1 (0.51) | ALDH1A1BACE1LMNAMAPTPOLB | |
| SCHEMBL1219325 | 0.80 | LMNA (0.43) | ALDH1A1BACE1LMNAMAPTPOLB | |
| SCHEMBL1219324 | 0.80 | LMNA (0.43) | ALDH1A1BACE1LMNAMAPTPOLB | |
| SCHEMBL3220878 | 0.79 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1BACE1LMNACA9 | |
| SCHEMBL15062110 | 0.79 | MAPT (0.42) | ALDH1A1L3MBTL1BACE1LMNAMAPT | |
| SCHEMBL14712980 | 0.79 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1BACE1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050069555-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050069555-A1 | Thiosemicarbazones as anti-virals and immunopotentiators | MAVS, IRF3, HAVCR2 | ALDH1A1 1173/4885L3MBTL1 3686/4885BACE1 4638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.