SCHEMBL6440984

SCHEMBL6440984

CS(=O)(=O)NC(=O)[C@@H](c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCCC1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 20/20 0.73
HDAC6 Q9UBN7 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6440982 1.00 ALOX5 (0.73) ALOX5HDAC6
SCHEMBL30209466 1.00 ALOX5 (0.73) ALOX5HDAC6
SCHEMBL8892800 0.89 ALOX5 (0.78) ALOX5HDAC6
SCHEMBL9315247 0.88 ALOX5 (0.80) ALOX5HDAC6
SCHEMBL9303393 0.87 ALOX5 (0.75) ALOX5HDAC6
SCHEMBL8895036 0.87 ALOX5 (0.75) ALOX5HDAC6
SCHEMBL9301897 0.86 ALOX5 (0.77) ALOX5HDAC6
SCHEMBL8892164 0.86 ALOX5 (0.75) ALOX5HDAC6
SCHEMBL9431826 0.86 ALOX5 (0.80) ALOX5HDAC6
SCHEMBL8827857 0.86 ALOX5 (0.80) ALOX5HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637961-A4 METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE WITH LEUKOTRIENE SYNTHESIS INHIBITORS. MILES INC (US) 1995-08-09 EP claimed
EP-0637961-A1 METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE WITH LEUKOTRIENE SYNTHESIS INHIBITORS Bayer Corporation (US) 1995-02-15 EP claimed
WO-1994018976-A1 METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE WITH LEUKOTRIENE SYNTHESIS INHIBITORS MILES INC. (US) 1994-09-01 WO claimed
EP-0593976-A1 Crystalline (R)-(-)-2-cycloheptyl-N-methylsulfonyl-4-(2-quinolinyl-methoxy)-phenyl-acetamide BAYER AG (DE) 1994-04-27 EP claimed
JP-6192228-A None JP disclosed
JP-6192228-A None JP disclosed
US-12629379-B2 Pharmaceutical composition for preventing, suppressing, or treating symptom associated with allergic reaction NIPPON CHEMIPHAR CO., LTD. (JP) 2026-05-19 US disclosed
US-20260000678-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING, SUPPRESSING, OR TREATING SYMPTOM ASSOCIATED WITH PSEUDO-ALLERGIC REACTION TAKASAKI UNIV OF HEALTH AND WELFARE (JP) 2026-01-01 US disclosed
US-12233071-B2 Medicament for treating cough NIPPON CHEMIPHAR CO., LTD. (JP) 2025-02-25 US disclosed
EP-4501357-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR SUPPRESSING OR TREATING SYMPTOMS ACCOMPANYING PSEUDO-ALLERGIC REACTIONS Takasaki University of Health and Welfare (JP) 2025-02-05 EP disclosed
CN-119233829-A Pharmaceutical composition for preventing, inhibiting or treating symptoms associated with pseudoallergy 学校法人高崎健康福祉大学 2024-12-31 CN disclosed
WO-2023190826-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR SUPPRESSING OR TREATING SYMPTOMS ACCOMPANYING PSEUDO-ALLERGIC REACTIONS 学校法人 高崎健康福祉大学 2023-10-05 WO disclosed
US-5391555-A Administering 2-(4(2-quinolinyl-methoxy)-phenyl)-acetic acid derivatives; Crohn's disease MILES INC. (US) 1995-02-21 US disclosed
EP-0637961-A1 METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE WITH LEUKOTRIENE SYNTHESIS INHIBITORS Bayer Corporation (US) 1995-02-15 EP disclosed
WO-1994018976-A1 METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE WITH LEUKOTRIENE SYNTHESIS INHIBITORS MILES INC. (US) 1994-09-01 WO disclosed
JP-H06192228-A CRYSTALLINE (R)-(-)-2-XYCLOHEPTYL-N-METHYLSULFONYL-(4-(2-QUINOLINYLMETHOXY)-PHENYL)-ACETOAMIDE BAYER AG 1994-07-12 JP disclosed
JP-H06192228-A CRYSTALLINE (R)-(-)-2-XYCLOHEPTYL-N-METHYLSULFONYL-(4-(2-QUINOLINYLMETHOXY)-PHENYL)-ACETOAMIDE BAYER AG 1994-07-12 JP disclosed
EP-0593976-A1 Crystalline (R)-(-)-2-cycloheptyl-N-methylsulfonyl-4-(2-quinolinyl-methoxy)-phenyl-acetamide BAYER AG (DE) 1994-04-27 EP disclosed
EP-0593976-A1 Crystalline (R)-(-)-2-cycloheptyl-N-methylsulfonyl-4-(2-quinolinyl-methoxy)-phenyl-acetamide BAYER AG (DE) 1994-04-27 EP disclosed
EP-0593976-A1 Crystalline (R)-(-)-2-cycloheptyl-N-methylsulfonyl-4-(2-quinolinyl-methoxy)-phenyl-acetamide BAYER AG (DE) 1994-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12233071-B2 Medicament for treating cough P2RX4, P2RX3, P2RX5 ALOX5 1345/4885HDAC6 897/4885
US-12629379-B2 Pharmaceutical composition for preventing, suppressing, or treating symptom associated with allergic reaction HRH2, HRH4, HRH1 ALOX5 600/4885HDAC6 963/4885
US-20260000678-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING, SUPPRESSING, OR TREATING SYMPTOM ASSOCIATED WITH PSEUDO-ALLERGIC REACTION TRPV1, TRPV4, TRPV5 ALOX5 696/4885HDAC6 2904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.