SCHEMBL6441490

SCHEMBL6441490

CC1=C(c2ccccc2)c2c(C(C)C)ccc(C)c2C1(Cl)[SiH2]C1(Cl)C(C)=C(c2ccccc2)c2c(C(C)C)ccc(C)c21.[Zr]

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4329726 0.80
SCHEMBL4062414 0.71 ROCK2 (0.32)
SCHEMBL5178882 0.71 FABP4 (0.33)
SCHEMBL4066830 0.66 LMNA (0.32) TSHR
SCHEMBL4061870 0.66 SLC6A2 (0.32)
SCHEMBL4054488 0.65 MAPT (0.34) ALDH1A1
SCHEMBL8134144 0.63 GABRA1 (0.42) ALDH1A1TSHR
SCHEMBL3356015 0.63 LMNA (0.32) TSHR
SCHEMBL7646165 0.62 MAPT (0.34) ALDH1A1
SCHEMBL4315247 0.62 MAPT (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1275670-B1 OLEFIN BLOCK COPOLYMERS, PRODUCTION PROCESSES OF THE SAME AND USE THEREOF MITSUI CHEMICALS INC (JP) 2005-08-10 EP disclosed