Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443407 | 0.86 | GAA (0.34) | NPC1LMNAPOLBRAB9AJAK2 | |
| SCHEMBL6441993 | 0.80 | KDM4E (0.47) | KDM4ESMN1; SMN2HTTALDH1A1NPC1 | |
| SCHEMBL31715017 | 0.74 | MAPT (0.44) | KDM4ESMN1; SMN2HTTALDH1A1NPC1 | |
| SCHEMBL29543930 | 0.68 | GABRG2 (0.36) | JAK2JAK1 | |
| SCHEMBL6445476 | 0.68 | CNR2 (0.43) | — | |
| SCHEMBL18138237 | 0.67 | RORC (0.37) | KDM4ESMN1; SMN2ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL6472572 | 0.66 | ACSS2 (0.33) | KDM4ESMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2704966 | 0.66 | KMT2A (0.46) | KDM4ESMN1; SMN2HTTALDH1A1MEN1 | |
| SCHEMBL3996358 | 0.66 | NOS1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL19256045 | 0.65 | ALDH1A1 (0.39) | KDM4ESMN1; SMN2HTTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556389-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039814-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2004-05-13 | — | — | WO | disclosed |