SCHEMBL644322

SCHEMBL644322

CC(C)(C)OC(=O)c1cc(OC(C)(C)C)c(CBr)c(OC(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34
STAT3 P40763 2/20 0.33
ALOX15 P16050 1/20 0.33
SERPINE1 P05121 2/20 0.32
SRD5A1 P18405 1/20 0.32
MTNR1A P48039 2/20 0.31
MTNR1B P49286 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4972623 0.80 ESR1 (0.52) CYP1A2CYP2D6CYP2C19
SCHEMBL4210382 0.78 TDP1 (0.51)
SCHEMBL15876193 0.76 SLC7A5 (0.46) SLC7A5CA12CA1CA2CA9
SCHEMBL20241781 0.76 SLC7A5 (0.46) SLC7A5CA12CA1CA2CA9
SCHEMBL7058435 0.74 CA12 (0.47) SLC7A5CA12CA1CA2CA9
SCHEMBL9197504 0.71 MTNR1A (0.46) CA12CA1CA2CA9CA14
SCHEMBL733017 0.71 TSHR (0.42) MTNR1AMTNR1B
Propionic Acid SCHEMBL6033471 0.71 SLC7A5 (0.42) SLC7A5CA12CA1CA2CA9
SCHEMBL4518140 0.71 GABRA1 (0.43) SLC7A5CA12CA1CA2CA9
SCHEMBL9640448 0.70 SLC7A5 (0.35) SLC7A5CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119103-B2 Bifunctional resorcinol, thioresorcinol, and dithioresorcinol derivative metal chelating conjugates MALLINCKRODT LLC (US) 2012-02-21 US disclosed
US-20090082324-A1 Bifunctional Resorcinol, Thioresorcinol, and Dithioresorcinol Derivative Metal Chelating Conjugates INFACARE PHARMACEUTICAL CORPORATION 2009-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090082324-A1 Bifunctional Resorcinol, Thioresorcinol, and Dithioresorcinol Derivative Metal Chelating Conjugates SPR, QDPR, SLC40A1 SLC7A5 696/4885CA12 1865/4885CA1 2526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.