Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | CLPP | Q16740 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443458 | 0.94 | CTSL (0.47) | CTSLCTSSCTSKCTSBITGB1 | |
| SCHEMBL6019599 | 0.90 | CTSL (0.52) | CTSLCTSSCTSKCTSBITGB1 | |
| SCHEMBL6443832 | 0.88 | CTSL (0.52) | CTSLCTSSCTSKCTSBITGB1 | |
| SCHEMBL6443194 | 0.87 | CTSB (0.51) | CTSLCTSSCTSKCTSBITGB1 | |
| SCHEMBL6019754 | 0.87 | CTSL (0.48) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6020789 | 0.86 | CTSL (0.65) | CTSLCTSSCTSKCTSBITGB1 | |
| SCHEMBL6021164 | 0.83 | CTSL (0.46) | CTSLCTSSCTSKCTSB | |
| SCHEMBL6446903 | 0.83 | CLPP (0.43) | CTSBITGB1ITGA4ITGB7CLPP | |
| SCHEMBL6021087 | 0.83 | CTSL (0.48) | CTSLCTSSCTSKCTSBCAPN1 | |
| SCHEMBL6445342 | 0.81 | CTSB (0.41) | CTSLCTSSCTSKCTSBCLPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | disclosed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |