Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.47 |
| ▸ | CTSK | P43235 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 9/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442556 | 0.89 | CTSS (0.58) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6442434 | 0.89 | POLB (0.45) | CTSSCTSKPOLBCTSLKDM4A | |
| SCHEMBL6446763 | 0.89 | ESR1 (0.41) | CTSSCTSKPOLBCTSLCTSB | |
| SCHEMBL6445439 | 0.88 | CTSS (0.56) | CTSSCTSKPOLBCTSLCTSB | |
| SCHEMBL6447305 | 0.88 | CTSS (0.43) | CTSSCTSKPOLBCTSLKDM4A | |
| SCHEMBL6446273 | 0.87 | CTSK (0.48) | CTSSCTSKPOLBCTSLKDM4A | |
| SCHEMBL6447648 | 0.86 | MTNR1A (0.40) | CTSSCTSKCTSLCTSBMEN1 | |
| SCHEMBL6443774 | 0.85 | NPC1 (0.55) | CTSSCTSKPOLBCTSLKDM4A | |
| SCHEMBL6445531 | 0.83 | NPC1 (0.60) | KDM4A | |
| SCHEMBL6443588 | 0.83 | NPC1 (0.51) | CTSSCTSKPOLBCTSLKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575903-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | Jerini AG (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004065353-A1 | COMPOUNDS FOR THE INHIBITION OF ROTAMASES | JERINI AG (DE) | 2004-08-05 | — | — | WO | claimed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | claimed |