Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14397902 | 0.83 | ALDH1A1 (0.46) | LMNAALDH1A1KDM4ESMN1; SMN2TSHR | |
| Acetic Acid SCHEMBL27629972 | 0.83 | FOLH1 (0.53) | ALDH1A1KDM4ESMN1; SMN2TSHRFOLH1 | |
| SCHEMBL8579457 | 0.82 | LMNA (0.46) | LMNAALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL254888 | 0.82 | HSD17B1 (0.48) | LMNAALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL3145510 | 0.82 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TSHRFOLH1HTT | |
| SCHEMBL1879310 | 0.82 | GABRA1 (0.43) | LMNAALDH1A1KDM4ESMN1; SMN2HPGD | |
| Methyl Alcohol SCHEMBL27864731 | 0.81 | FOLH1 (0.55) | LMNAALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL26162757 | 0.80 | GABRA1 (0.42) | LMNAALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL602386 | 0.80 | FOLH1 (0.59) | ALDH1A1KDM4ESMN1; SMN2TSHRFOLH1 | |
| SCHEMBL152624 | 0.80 | ALDH1A1 (0.50) | LMNAALDH1A1TSHRFOLH1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118745126-A | Synthesis method of p-chloromethyl styrene | 北京联本医药化学技术有限公司 | 2024-10-08 | — | — | CN | disclosed |
| EP-3960754-A2 | ALPHA4BETA7 INTEGRIN THIOETHER PEPTIDE ANTAGONISTS | Protagonist Therapeutics, Inc. (US) | 2022-03-02 | — | — | EP | disclosed |
| EP-3143037-B1 | ALPHA4BETA7 INTEGRIN THIOETHER PEPTIDE ANTAGONISTS | PROTAGONIST THERAPEUTICS INC (US) | 2021-06-23 | — | — | EP | disclosed |
| EP-1224195-B1 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2005-05-18 | — | — | EP | disclosed |
| EP-1224195-A1 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001027128-A1 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |
| WO-2000075094-A2 | METHOD FOR PRODUCING A HALOGENATED ACETOPHENONE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-12-14 | — | — | WO | disclosed |