Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | IAPP | P10997 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117424 | 0.84 | GABRA1 (0.64) | GABRA1GABRB2HMGB1IAPPALDH1A1 | |
| SCHEMBL3291708 | 0.82 | HMGB1 (0.62) | HMGB1ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL11347621 | 0.82 | GABRA1 (0.45) | GABRA1GABRB2HMGB1IAPPALDH1A1 | |
| SCHEMBL6445870 | 0.82 | LMNA (0.43) | ALDH1A1LMNAHTTKDM4EMAPT | |
| SCHEMBL1367671 | 0.81 | ALDH1A1 (0.39) | GABRA1GABRB2HMGB1IAPPALDH1A1 | |
| SCHEMBL9263627 | 0.80 | SMN1; SMN2 (0.40) | GABRA1GABRB2HMGB1IAPPALDH1A1 | |
| SCHEMBL8124725 | 0.79 | PRKCI (0.54) | GABRA1GABRB2HMGB1IAPPALOX5 | |
| SCHEMBL28035846 | 0.79 | AKR1B1 (0.52) | GABRA1GABRB2HMGB1IAPPALDH1A1 | |
| SCHEMBL31346667 | 0.79 | AKR1B1 (0.52) | GABRA1GABRB2HMGB1IAPPALDH1A1 | |
| SCHEMBL26162757 | 0.79 | GABRA1 (0.42) | GABRA1GABRB2ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820200-A | Heterobivalent compound taking piperidinoindenone-salicylic acid as parent, and preparation method and application thereof | 合肥工业大学 | 2024-04-05 | — | — | CN | claimed |
| CN-120117987-A | Arylalkanoic acid phloroglucinol ester compound, preparation method and application thereof | 南华大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-118978524-A | Nitrazonit derivative and medical application thereof | 绍兴君科臻元医药科技有限公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-112480104-B | Nitrazonit derivative and medical application thereof | 绍兴君科臻元医药科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-117820200-A | Heterobivalent compound taking piperidinoindenone-salicylic acid as parent, and preparation method and application thereof | 合肥工业大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-115154401-B | Anti-inflammatory and soothing emulsion and preparation method thereof | 武汉诺安药业有限公司 | 2023-10-10 | — | — | CN | disclosed |
| US-20210353579-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO LTD (CN) | 2021-11-18 | — | — | US | disclosed |
| EP-3279182-B1 | ACETYLSALICYLIC ACID DERIVATIVE CRYSTAL AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG YUEJIA PHARMACEUTICALS CO LTD (CN) | 2021-05-26 | — | — | EP | disclosed |
| US-10882817-B2 | Acetylsalicylic acid derivative crystal, its preparation method and use | ZHEJIANG YUEJIA PHARMACEUTICALS CO., LTD (CN) | 2021-01-05 | — | — | US | disclosed |
| CN-109422788-B | Preparation method of cytarabine hydrochloride | 北京斯利安药业有限公司 | 2020-11-20 | — | — | CN | disclosed |
| EP-0483881-B1 | 3-Amidoindolyl derivatives | MERRELL PHARMA INC (US) | 1998-01-21 | — | — | EP | disclosed |
| US-5686469-A | ANTIINFLAMMATORY AGENTS | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5506224-A | ADMINISTERING TO TREAT MAMMALIAN PATHOLOGIES INVOLVING MAST CELL DEGRANULATION AS CONSEQUENCE OF NEUROGENIC AND/OR IMMUNOGENIC HYPERSTIMULATION | LIFEGROUP S.P.A. (IT) | 1996-04-09 | — | — | US | disclosed |
| EP-0513285-B1 | IMIDAZOL-2-YL DERIVATIVES OF SUBSTITUTED BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | PHARMACIA SPA (IT) | 1996-01-24 | — | — | EP | disclosed |
| US-5356920-A | Anticholesterol, antilipemic agent | FARMITALIA CARLO ERBA SRL. (IT) | 1994-10-18 | — | — | US | disclosed |
| EP-0610745-A2 | Novel aminomethylene derivatives as immunosuppressants | Bayer Corporation (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1992009582-A1 | IMIDAZOL-2-YL DERIVATIVES OF SUBSTITUTED BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA SRL (IT) | 1992-06-11 | — | — | WO | disclosed |
| US-4985440-A | Hypolipidaemic imidazol-2-yl-derivatives of bicyclic compounds | FARMITALIA CARLO ERBA, S.R.L. (IT) | 1991-01-15 | — | — | US | disclosed |
| EP-0375746-A1 | HYPOLIPIDAEMIC IMIDAZOL-2-YL-DERIVATIVES OF BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-07-04 | — | — | EP | disclosed |
| WO-1989008646-A1 | HYPOLIPIDAEMIC IMIDAZOL-2-YL-DERIVATIVES OF BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10882817-B2 | Acetylsalicylic acid derivative crystal, its preparation method and use | ACMSD, SSB, NFKBIA | GABRA1 1454/4885GABRB2 2132/4885HMGB1 1323/4885 |
| US-20210353579-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | HPGDS, PTGIS, PTGES | GABRA1 3682/4885GABRB2 4131/4885HMGB1 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.